Osteoparosis Flashcards

1
Q

Normal bone health

A

Balance between Osteoclasts breaking down old bone, osteoblasts forming new bone
Peak bone mass - around 30s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Early bone loss (osteopenia)

A

Bone remodelling imbalanced- bone reabsorption out pacing bone formation
Trabecular bone found in vertebrae and ends of long bone
Bone mineral density (BMD) begins to decline
Osteopenia BMD - -1.0 & -2.5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Established osteoporosis

A

Significant loss of bone mass
Bone becomes fragile and more susceptible to fractures under minimal or normal forces
Confirmed osteoparosis - BMD score is -2.5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Severe osteoporosis

A

Extreme loss of bone density
Bone becomes fragile highly brittle, unable to withstand minor stresses
Deformities and chronic complications
Multiple fractures can occur with poor healing, reduced functionality

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is it?

A

Osteoporosis is a systemic skeletal disorder characterized by low bone mass and deterioration of bone tissue, resulting in increased bone fragility and a higher risk of fractures. It progresses silently over time, often remaining undetected until a fracture occurs.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Essential vitamins and minerals

A

Calcium: Essential for maintaining bone density. Deficiency increases bone fragility.
Vitamin D: Facilitates calcium absorption in the gut and its incorporation into bones.
Magnesium: Plays a role in bone formation and influences parathyroid hormone (PTH) activity.
Vitamin K2: Regulates calcium deposition, directing it into bones rather than soft tissues.
Phosphorus: Excess or deficiency can weaken bones, as a balance with calcium is crucial.
Protein: Necessary for collagen synthesis, which forms the bone matrix

How well did you know this?
1
Not at all
2
3
4
5
Perfectly