Osteomyelitis

Question 1

What is osteomyelits?

Answer 1

bone infection (periosteium, cortical, medullary)

Question 2

What are the 6 causes of of osteomyelits?

Answer 2

1. trauma
2. any infection directly enter the bone marrow or in the body carried by the blood to the bone
3. intravenous drug users
4. artificial joints, prosthetic bone devices,
5. poor circulation
6. weakened immune system

Question 3

What is the most common cause of acute osteomyelitis?

Answer 3

• 80-90 % staph aureus

H. influenza and Group B. Strep

Question 4

What is a “Brodie abcess”, seen in acute osteomyelitis?

Answer 4

small multiple intraosseous abscesses (cortex)

Question 5

What is “sequestrum” (destroyed bone)?

Answer 5

segmental necrosis of the bone

Question 6

What is involucrum?

Answer 6

new reactive bone around the necrotic bone

Question 7

5-25% of acute osteomyelitis persists as what?

Answer 7

chronic infection

Question 8

What imaging indicates an infected bone?

Answer 8

MRI or CT

Question 9

What method of diagnosis uses technetium-99 (absorbed by tumor)?

Answer 9

radionuclide bone scan

Question 10

What is an aspiration culture?

Answer 10

(gram stain + culture and sensitivity)

Question 11

What is tuberculous osteomyelitis (Pott’s disease)?

Answer 11

a chronic granulomatous osteomyelitis

• spine is most common
• in developing countries most cases under 25

Question 12

Patients with tuberculous osteomyelitis present with what?

Answer 12

• low grade fever, chills, and weight loss
• pain with motion
• localized tenderness
• rediculopathy

Question 13

Lesions in tuberculous osteomyelitis

Answer 13

solitary but might be multifocal in immunosuppressed

Question 14

histopathology in tuberculous osteomyelitis

Answer 14

lymphocytic inflitrate

Question 15

congenital syphilis starts when?

Answer 15

5th month of gestation

Question 16

congenital syphilis is due to what?

Answer 16

complication of adult type (tertiary stage is 2-5 years after primary)