Osteomalacia Flashcards

1
Q

What is Osteomalacia

A

Defective bone mineralisation causing soft bones. Results for insufficient vitamin D

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1
Q

How is Vitamin D created?

A

From cholesterol by skin in response to UV radiation

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2
Q

Who is at higher risk of vitamin d deficiency?

A

Malabsorption disorders eg IBD
Chronic Kidney Disease

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3
Q

What is Vitamin D essential for in absorption?

A

Calcium and Phophate absorption in intestines and reabsorption in kidneys

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4
Q

Low calcium can lead to what happening to parathyroid hormone?

A

Increased parathyroid hormone causing secondary hyperparathyrodism

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5
Q

Investigations for Osteomalacia?

A

Serum 25 hydroxyvitamin D
Bloods for Calcium, Phosphate and Alk Phos and Parathyroid Hormone

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6
Q

What may xrays show in osteomalacia?

A

Osteopenia (radiolucent bones)

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7
Q

Treating Osteomalacia?

A

Colcacliferol (Vitamin D3)

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