Gout Flashcards

1
Q

What is Gout?

A

Type of Crystal Arthropathy associated with chronically high blood uric acid levels

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2
Q

Critical differential diagnosis for Gout presentation?

A

Septic Arthritis

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3
Q

Risk factors for Gout?

A

Male
Family History
Obese
High Purine Diet
Alcohol
Diuretics
CV Disease
Kidney Disease

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4
Q

Most commonly affected joints in Gout?

A

Base of Big Toe: Metatarsophalngeal Joint
Base of Thumb: Carpometacarpal Joint
Wrist

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5
Q

Diagnosis of Gout

A

Clinically
raised Serum Urate Level
Aspirated Joint fluid: monosodium urate crystals needle shaped and negatively birefringent of polarised light

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6
Q

Xray signs for Gout?

A

Maintained joint space (no loss of joint space)
Lytic lesions in bone
Punched out erosions
Erosions can have sclerotic borders with overhanging edges

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7
Q

Management of Gout?

A

NSAIDS eg Naproxen with PPI
Colchcine 2nd Line
Pred 3rd Ljine

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8
Q

Gout Prophylaxis?

A

Xanthine Oxidase Inhibitors eg Allopurinol or Febuxostat

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