Osteogenesis Imperfecta Flashcards
1
Q
What is the inheritance of OI?
A
AD OI types I to V
AR OI types VII
2
Q
Which type is lethal in the newborn period?
A
OI type II
3
Q
What are the clinical manifestations of OI?
A
- Fractures of various ages and stages of healing
- Wormian bones
- Vertebral compression fractures
- Osteopenia
- Abnormal dentition incld. brown or gray teeth and weak teeth
- Progressive hearing loss
- Blue-coloured sclerae
- Ligamentous laxity
