MERRF Flashcards
1
Q
What is the inheritance for MERRF?
A
Mitochondrial
2
Q
What are the clinical features of MERRF?
A
- Myoclonus –> seizures, ataxia, weakness –> dementia
- Hearing loss
- Normal early childhood development
- Short stature
- Optic atrophy
- Pigmentary renal changes
- Abnormal fat distribution
- Cardiomyopathy
- WPW syndrome
- Elevated lactate and pyruvate
