Osteoarticular 4 Flashcards
4 major forms of Arthritis
- inflammatory arthritis
- Non inflammatory arthritis
- Reactive arthritis
- Degenerative arthritis
lab findings in arthritis
increased WBCs as you go up
noninflam- 50-2000WBCs
mildly-0-9000
sev-100-160000
purulent- 150-250000 WBCs
predisposing features of osteoarthritis
pagets
gout
acromegaly
-majority no obvious predisposing
jts involved in osteoarthritis
- weight bearing
- lower lumbar vert
- cervical vert
- PIPS/DIPS
gross morphology
- eburnation
- subchondral cysts
- osteophytes
- osteophytic outgrowths
- jt mce
microscopic findings in OA
fibrilation of cartilage
What is the theater sign
pain and knee jt locking when arising from a prolonged seated pos.
how many jts does reactive arthritis affect
inflammation of fewer than 5 jts
what is reiters syndrome triad
- inflammation of large jts
- conjuctivitis
- urthethritis
blood markers in reactive arthritis
RF neg
HLA B27
Causitive infections of reactive arthritis
campylobacter, salmonella, shigella, clymedia, neissria
what are enthesitis related to and what is the primary site
inflammatory autoimmune diseases (RA, Psoriasis, IBD, Rieters)
calcaneal tendon
common cause of infective arthritis
lyme disease- arthritis due to spirochetes
4 major causes of gout
- increased production
- increased cell turnover
- decreased salvage of dietary purines
- reduced excretion
2 major causes of primary gout and causes
- Impairement of renal uric acid 85%
2. overproduction of uric acid 15%
