Osteoarthritis and joint replacement Flashcards
What are the signs and symptoms of osteoarthritis?
- Pain
- Stiffness
- Loss of range of movement
- Deformity
- Loss of function
- Reduced quality of life
What is osteoarthritis?
- Degenerative disease of the synovial joints
* Progressive loss of cartilage
What are the modifiable risk factors of osteoarthritis?
- Trauma
- Muscle weakness
- high impact activities
What are the non modifiable risk factors of osteoarthritis?
- Sex: female>males
- Age
- Genetics
- Congenital
What are the acquired risk factors of osteoarthritis?
- Infection
- Dysplasia
- SCFE: slipped capital femoral epiphysis
- Perthes
Water content in ageing vs osteoarthritis
In ageing, water content is decreased, it is increased in osteroarthritis
Collagen in ageing vs osteoarthritis
Same in ageing, disorganised in osteoarthritis
Proteoglycan synthesis in ageing vs osteoarthritis
Same in ageing, increased in osteoarthritis
Proteoglycan content in ageing vs osteoarthritis
Decreased in both
Chondrocyte size in ageing vs osteoarthritis
Increased in ageing, same in osteoarthritis
Chondrocyte number in ageing vs osteoarthritis
Decreased in ageing, same in osteoarthritis
Modulus of elasticity in ageing vs osteoarthritis
Increased in ageing, decreased in osteoarthritis
Describe the examination in suspected osteoarthritis
- Inspection: BMI, gait, leg length, scars
* ROM: active and passive
What is seen on X ray in osteoarthritis?
- Joint space narrowing
- Sclerosis
- Subchondral cysts
- Marginal osteophytes
What is the non operative management of osteoarthritis?
- Analgesia: paracetamol, 1st line opiate, NSAID, topical
- Lifestyle modification: weight loss, exercise program
- Corticosteroid infection
- Viscoelastic injection
- Glucosamine/chondroitin supplements
- Stem cell therapy