Osteoarthritis

Question 1

Determinants of OA (14)

Answer 1

• increasing age
• females
• european
• disability
• genetics
• obesity
• diet
• bone metabolism
• joint injury
• joint alignment
• muscle strength
• physical activity
• occupation
• leg inequality

Question 2

Pathophysiology of OA (8)

Answer 2

• degradation of articular cartilage
• sclerosis of subchondral bone
• osteophyte formation
• synovial inflammation
• ligament dysfunction
• meniscus damage in knee
• hypertrophy of joint capsule
• change in peri-articular muscles (eg. atrophy)

Question 3

Clinical Features of OA (8)

Answer 3

• Joint unilateral pain
• Tenderness
• Morning stiffness <30 minutes
• Decreased ROM
• Strength loss
• Crepitus
• Inflammation
• Swelling