Osseous Surgery: Regeneration- Review Flashcards
Tissue transferred from one site to another in the SAME individual:
Autograft
Tissue trasnferred between individuals of the SAME SPECIES:
Allograft
- free-dried bone
- demineralized freeze-dried bone
- solvent treated
All of the following are:
Allograft
INERT material used for graft:
alloplast
- calcium sulfate
- calcium phosphates
- HTR
- Bioactive glass ceramics
- SRM
all of these are types of:
alloplasts
Tissue transferred between individuals of DIFFERING SPECIES:
Xenograft
- bovine bone
- bovine bone + cell-binding peptide-15
- fetal pig enamel matrix derivative
all of these are types of:
Xenografts
Combination of grafts:
composite
25% hydroxyapatite and 75% freeze dried bone is an example of:
composite graft
Bone sources for grafting can be:
intraoral or extraoral
Intraoral sources for bone grafting include:
- cortcal bone chips
- osseous coagulum
- healing extraction socket
- chin or ramus block graft
Extraoral sources for bone grafting:
- iliac crest
- ribs
When calcium sulfate is added to FDBA:
CaSO4 regeneraton
In CaSO4 regeneration, what is added to FDBA?
calcium sulfate
What is the rationale behind CaSO4 regeneration?
Calcium sulfate binds bone particles to prevent bone washout and also accelerates bone formation by enhancing BMP and providing a source of calcium ions to aid in mineralization
Indications for regeneration/bone replacement grafts:
- deep vertical defects
- esthetic considerations
- teeth critical to prosthesis
- when anatomy precludes other procedures
- GTR
Contraindications for regeneration/bone replacement grafts:
- poor plaque control
- medically compromised
- poor maintenance compliance
Advantages of regeneration/bone replacement grafts:
- restores lost periodontal tissue
- maintains teeth in healthy functional state
- enhances long term prognosis of teeth
Disadvantages of regeneration/bone replacement grafts:
- technique and material sensitive
- expensive
- may require 2 surgeries
- unpredictable outcome
- requires ideal wound closure
- longer/more frequent post-op care
- send surgical site sometimes required
- success decreases significantly in furcation
- defect dependent
- expensive
Connective tissue is the coding to determine the type of tissue you obtain from a graft. Free gingival grafts will end up revascularizing with the underlying connective tissue. This is the ____ to bone graft replacement
Biologic response
What is the coding to determine the type of tissue you obtain from a graft.
connective tissue
T/F: Free gingival grafts will end up revascularinzing with the underlying connective tissue:
true
Biologic response when viable osteoBLASTS are replaced
osteogenic
Scaffold for bone formation (freeze-dried bone allograft, bioactive glass):
osteoconductive
Release of material to induce bone formation:
osteoinductive
Production of bone by a biologic mechanism:
osteoproductive
1.viable osteoblasts are transplanted
2. scaffold for bone formation
3. release of material to induce bone formation
4. production of bone by a biologic mechanism
- osteogenic
- osteoconductive
- osteoinductive
- osteoproductive
Describe the healing sequence:
- Incorporation (clot formation)
- Revascularization
- Resorption of graft material with slow release of BMP to induce bone formation
- Bone formation
- Bone remodeling and maturation
Graft success is dependent on:
defects
What type of defects have little to no success with grafts?
horizontal bone loss (suprabony defects)
List in order the success rates of infra bony defects (most to least successful)
- 3 walled
- 2 walled
- 1 walled
List some complications of grafting:
- no regeneration
- sequestra
- root resorption (rare)
- donor site problems (at second site)
- infection (less than 1%)
Variables that can affect grafting success include:
- pre-scaling or scaling at time of surgery
- local drug delivery before surgery
- flap design
- intramarrow penetration
- hydration of graft material
- root treatment or m modification
- use of antibiotics
- endodontics & graft success
- smoking & graft success