Osmoregulation and Excretion Flashcards

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1
Q

What is osmoregulation?

A

This is the homeostatic process by which animals control their solute concentrations and balance water gain and loss.

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2
Q

What is the general adaptation of freshwater mammals to osmoregulate?

A

Reduction in uptake of water and conservation of solutes.

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3
Q

What is the environment that desert and marine animals live in described as?

A

DESICCATING ENVIRONMENT - it can quickly deplete them of their body water.

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4
Q

What is excretion?

A

This is the process animals use to remove nitrogenous wastes from their bodies.

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5
Q

What is osmosis?

A

This is the movement of water across a selectively permeable membrane from a region of low solute concentration to an area of high solute concentration.

OR

from a region of HIGHER FREE WATER CONCENTRATION to a region of LOWER FREE WATER CONCENTRATION.

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6
Q

What is osmolarity?

A

The solute concentration in a solution, this determines the direction of water movement across a selectively permeable membrane.

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7
Q

When two solution differ in osmolarity, what is the net flow of water?

What happens if the solutions are isoosmotic?

A

Hypoosmotic (lower solute concentration) to the hyperosmotic (higher solute concentration).

If isoosmotic: water movement is equal in both directions.

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8
Q

What are the two ways that an animal can maintain its water balance? Example?

A
  1. Osmoconformer - these are isoosmotic to their environment and do not regulate their osmolarity. All osmoconforming animals are marine, NOT ALL MARINE ARE OSMOCONFORMERS.
  2. Osmoregulators - expend energy to control water uptake and loss in environments with varying osmolarity. These include freshwater and terrestrial animals.
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9
Q

What is meant when i say that most animals are stenohaline?

A

This means that they cant tolerate substantial changes in external osmolarity.

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10
Q

What is meant when I say that some animals are euryhaline?

A

This means that the animal can survive large fluctuations in external osmolarity. Such as barnacles that can handle tidal fluctuations or salmon that live in oceans but travel up freshwater rivers to reproduce.

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11
Q

How do most marine invertebrates osmoregulate?

A

Osmoconformers

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12
Q

Even though marine invertebrates (osmoconformers) dont face any substantial challenges in water balance, do they still need to be able to transport certain solutes to maintain homeostasis?

A

YES

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13
Q

How do most marine vertebrates osmoregulate?

A

Osmoregulation

some marine invertebrates are osmoregulators as well.

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14
Q

In comparison to sea water, what is the solute concentration of bony fishes?

A

hypoosmotic.

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15
Q

Since marine bony fish are hypoosmotic to their sea water environment, what happens to their body water? How do they balance their water loss? How do they regulate their body salt?

A

Their body water is lost via osmosis to the hypertonic sea water.

They gain their water back by drinking seawater and excreting the salts and small amount of water via urine.

Salt is gained by drinking sea water and is also diffused via food.

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16
Q

What is the osmolarity of sharks? How does sea wter act with sharks?

A

Sharks have an osmolarity that is very close to seawater.

The sea water will slowly enter the sharks body and is disposed via their kidneys.

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17
Q

What is the osmolarity of a freshwater animal (fish) to its environment? Where does water move? How do they lose their salts? How is salt replaced?

Euryhalines?

A

They are hyperosmotic. They take in water from environment via osmosis, excrete large amounts of water via urine to maintain water balance.

Salts are lost by diffusion and are replaced via foods and uptake across gills.

Salmon and other euryhaline fishes that migrate between seawater and freshwater undergo dramatic changes in osmoregulatory status.

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18
Q

What is anhydrobiosis, what is one exxample of an organism that undergoes this? What molecule aids in this process?

A

This is when some aquatic invertebrates in areas like temporary ponds lose almost all of their body water and survive in a dormant state.

Trehalose is a disaccharide that essentially replacing water that is normally associated with proteins.

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19
Q

What is a major problem in terrestrial plants and animals?

A

Dehydration

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20
Q

What are two ways in which we get our water? Look at this picture and see the differences in water uptake and water loss between a human and a desert animal.

A

Drinking and eating moist foods

Ultilizing metabolic water

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21
Q

How much of the resting metabolic rate goes to maintain osmotic gradients in osmoregulators? What does the cost depend on?

A

About 5-30% of resting metabolic weight

  1. Difference in animals osmolarity and its surroundings
  2. Ease of water moving across animals surface
  3. Work required to pump solutes across its membranes
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22
Q

What is transport epithelia?

A

These are specialized epithelial cells that regulate solute movement.

These are essential components of osmotic regulation and metabolic waste disposal.

Look at transitional epithelium and its role in salt secretion in the nasal glands of a marine bird.

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23
Q

Do animals tend to make different nitrogenous wastes depending on their environment? What are the 3 nitrogenous wastes we discuss? Which is the most toxic? Least toxic?

A

YES

Urea, ammonia, and uric acid

Ammonia is the most toxic of the nitrogenous waste products.

Urea is the least toxic.

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24
Q

What is gout?

A

This is when uric acid deposits into the joints and causes pain and inflammation.

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25
Q

Look at this picture and understand what animals tend to excete which notrogenous waste.

A

26
Q

What are the 4 steps in which urine is produced?

A
  1. Filtration - pressure filtering water and small molecules into filtrate while cells and large molecules can’t pass.
  2. Reabsorption - reclaiming valuable solutes and water from the filtrate. (adjusting osmolarity)
  3. Secretion - adding toxins and other solutes from body fluids to the filtrate. (adjusting osmolarity)
  4. Excretion - elimination of filtrate from the system.
27
Q

Describe the protonephridia of a planarian. What does it consist of? Do these function in osmoregulation or nitrogenous waste removal?

A

These are filtration units of planarias. Consisting of a tubule cell and cap cell, there is cilia inside and all of these components together are what a “flame bulb” consists of. These tubulues end at an opening in the body wall to empty into the environment.

Mostly control osmoregulation, nitrogenous wastes are primarily removed through the mouth.

28
Q

Describe the metanephridia of an earthworm. Osmoregulation or nitrogenous waste removal?

A

These are located two in each segment of the earthworm.

Collect fluid from the coelom, to filter and excrete it through opening in body wall per each metanephridia.

These earthworms absorb nutrients and water directly through their skin, these metanephridia allow for them to control osmoregulation and excrete nitrogenous wastes

29
Q

Describe the Malpighian tubes of insects. Osmoregulation or nitrogenous waste removal?

A

These function in both osmoregulation and nitrogenous waste excretion.

Each tubule extends into the body cavity surrounded by hemolymph and absorbs salts, water, and nitrogenous bases and drains into the intestine where the urine and feces are both excreted through the anus.

30
Q

Do kidneys function in osmoregulation or nitrogenous waste excretion?

A

BOTH

31
Q

Which of the regions is outer and which is inner between the renal cortex and the renal medulla? What is the function of the renal pelvis?

A

Cortex - outer

Medulla - inner

The renal pelvis collects the urine before draining into the ureter.

32
Q

What are the functional units of the kidney called? What are the two types of these and their differences?

A

Nephrons.

Cortical - About 85% of nephrons, componenents only reside in the renal cortex.

Juxtamedullary - loop of henle descends into the renal medulla.

33
Q

What deos a nephron consist of?

A

A single long tubule and a ball of capillaries called a GLOMERULUS.

34
Q

What is a bowmans capsule?

A

This is a cup-shaped structure that surrounds the glomerulus and receives the filtrate from it.

35
Q

What does the renal corpuscle consist of?

A

Glomerulus and the Bowmans capsule.

36
Q

HOw is filttrate created in the renal corpuscle?

A

As the force of the blood pressure is exerted on the wall of the glomerulus the filtrate is pushed into the lumen of the bowmans capsule.

37
Q

What does filtrate consist of?

A

Water, salts, glucose, amino acids, nitrogenous wastes, and other small molecules.

38
Q

Describe the flow of filtrates after it leaves the bowmans capsule?

A

It goes through the proximal tubule

Then the loop of henle

Then the distal tubule

then the collecting duct

Then the renal pelvis

39
Q

Are the blood vessels other than the glomerulus a part of the nephron?

A

NO

40
Q

What is the difference between an afferent and an efferent arteriole? What is the peritubular capillary? Vasa recta? How do the vasa recta function with the loop of henle?

A

Afferent - leads to the glomerulus.

Efferent arteriole - leaves the glomerulus

Peritubular capillaries - form the the efferent arteriole and surround the proximal and distal tubules.

Vasa recta - These serve the loop of henle, function as a countercurrent system.

41
Q

What is the function of the prximal tubule in regards to the filtrate? What is its function in regards to pH? What happens to the concentration of the filtrate?

A

Reabsorption of components of filtrate such as sugars, ions, water, and other nutrients takes place here. Gows from the proximal tubule to the interstitial fluid then to the peritubular capillary.

Filtrate concentration increases

Maintenance of pH of body fluids occurs here.

42
Q

What is the function of the descending loop of henle? What happens to the concentration of filtrate here?

A

More water is reabsorbed via the aquaporins.

Filtrate becomes even more concentrated here.

43
Q

What is the function of the ascending loop of henle? What hapens to the concentration of the filtrate here?

A

NaCl leaves the tubule to help in maintenance of the interstitial fluid osmolarity

Filtrate becomes slightly more dilute.

44
Q

What is the function of the distal tubule?

A

Regulate the concentration of K+ and NaCl

Helps to regulate the pH of body fluids as well.

45
Q

What primarily contributes to the osmolarity of the filtrate in the collecting duct? What is is osmolarity in comparison to the body? Is this area under the control of hormones?

A

NaCl and urea

hyperosmotic in comparison to the body

YES, this area is under the control of hormones.

46
Q

How many liters of blood are filtered by the kidneys per day? How much filtrate is produced per day? What percentage of this is reabsorbed?

A

1600L of blood is filtrated

180L of filtrate is produced

99% of the filtrate is reabsorbed

47
Q

Look at this picture and understand what is going on in each area of the kidney, note the active and passive transportation.

A

aljkshdfg

48
Q

Is urine more concentrated than blood?

A

YES

It is 1200 mOsm in comparison to bloods 300 mOsm

49
Q

What 2 factors give the kidneys the ability to concentrate the urine so much?

A
  1. The precise arrangement of the loops of henle and collecting ducts.
  2. Active transport of NaCl out of the ascending limp of loop of henle
50
Q

What is the countercurrent multiplier system?

A

This is the type of countercurrent system in which energy is expended to establish a concentration gradient.

Look at this picture to understand the countercurrent multiplier system.

51
Q

What part of the brain detects changes in the osmolarity? What is secreted in response to a increase in osmolarity? Where is this secreted from? Where does this hormone act on? What does it cause?

A

Hypothalamus

ADH is released

Secreted from the posterior pituitary

Acts on the collecting duct, stimulating the insertion of aquaporins so water can be reabsorbed at a higher rate.

52
Q

What does alcohol do to the release of aDH?

A

It inhibits the release of ADH, this causes the excessive secretion of urinary water and leads to dehydration.

53
Q

What is DI? What causes this?

A

This is the copious excretion of dilute urine as a result of ADH deficiency or due to decreased renal sensitivity to ADH.

54
Q

Take a brief look at this picture of the pathway ADH action within a collecting duct cell.

A

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55
Q

What is the Juxtaglomerular apparatus? Where is it located? What system does it play a role in?

A

This is a group of cells located at the afferent arteriole that detect changes in blood volume and blood pressure. They play a role in the RAAS.

56
Q

Describe the RAAS starting with a drop in the BP of blood volume.

A

JGA detects this drop and releases renin into the bloodstream.

renin interacts with angiotensinogen (secreted by liver) to make angiotensin I

Angiotensin I is converted to angiotensin II by ACE (angiotensin converting enzyme)

Angiotensin II constricts arterioles and also stimulates the release of aldosterone

Aldosterone increases salt and water resorption

57
Q

What do ACE inhibitors do?

A

Inhibit ACE from coverting angiotensin I to angiotensin II

58
Q

What do ADH and RAAS both do? Which one of these is the only one that will respond to a decrease in blood volume?

A

Both increase the reabsorption of water

Only RAAS will respond to decrease in blood volume.

59
Q

What hormone opposes RAAS? Where does this come form? What does it do?

A

ANP (atrial natriurietic peptide).

This is released from the atria of the heart in response to an increase in blood volume and blood presure

Which inhibits the release of renin and aldosterone and inhibits the reabsorption of NaCl by the collecting ducts.

60
Q

RAAS does what to bp and ANP does what to BP?

A

RAAS - increase BP

ANP - decrease BP