OSLER-RENDU-WEBER SYNDROME

Question 1

CONCEPT

Answer 1

HEREDITARY MUCOCUTANEOUS DISORDER CHARACTERIZED BY NUMEROUS SPIDER-LIKE TELANGIECTASIA AND ARTERIOVENOUS FISTULA (LIVER AND LUNGS)

Question 2

CLINICALLY

Answer 2

INTERNAL ORGANS TO THE FACE, NECK, CHEST, LIPS, GINGIVA, BUCCAL MUCOSA, TONGUE

Question 3

CHARACTERISTICS

Answer 3

• SMALL DILATED ARTERIES NEAR THE SURFACE OF THE SKIN OR MUCOUS MEMBRANE (1-3 mm)
• NOSEBLEEDS

Question 4

SYMPTOMES

Answer 4

TELANGIECTASIA ARE FRAGILE AND RUPTURE AT TIMES CAUSING GI BLEEDING, IRON DEFICIENCY ANEMIA AND HEMATURIA