Orthopedic Anesthesia Flashcards
What are the two biggest factors associated with development of osteoporosis?
- Elderly age
- Menopause
What hormonal changes are characteristic of osteoporosis?
- ↑ PTH
- ↓ Vit D
- ↓ HGH
- ↓ Insulin-like growth factors
What are the four most common meds used to treat osteoporosis?
dronate drugs
- Fosamax (Alendronate)
- Actonel (Risedronate)
- Boniva (Ibandronic Acid)
- Reclast (Zoledronate)
Differentiate between Bouchard’s nodes and Heberden’s nodes.
- Bouchard’s = proximal interphalangeal joints
- Heberden’s = distal interphalangeal joints
What drug is the most common chondroprotective agent that helps protect the articular joint?
Glucosamine
What anesthetic considerations should be given to glucosamine?
Glucosamine needs to be stopped two weeks prior to surgery due to PLT aggregation inhibition.
Arthritis characterized by morning stiffness that improves throughout the day is….
Rheumatoid arthritis
Arthritis that is characterized by worsening symptoms throughout the course of the day is…
Osteoarthritis
What labs are typically elevated in a patient with rheumatoid arthritis?
- ↑ Rheumatoid factor (RF)
- ↑ Anti-immunoglobulin antibody
- ↑ C-reactive protein (CRP)
- ↑ Erythrocyte Sedimentation Rate (ESR)
What common dose of stress dose glucocorticoid is used for RA patients?
50mg hydrocortisone (Solu-cortef)
What two TNFα inhibitors are commonly used to treat RA?
- Infliximab
- Etanercept
Which of the following drugs treat RA?
- Methotrexate
- Hydroxychloroquine
- Sulfasalazine
- Leflunomide
Trick question. All of them do
- Methotrexate
- Hydroxychloroquine
- Sulfasalazine
- Leflunomide
What airway concerns should be considered with RA patients?
- Limited TMJ movement
- Narrowed glottic opening
- Cricoarytenoid arthritis
Where is the most instability typically located in the cervical spine of RA patients?
Atlantoaxial Junction
(be careful not to displace the odontoid process and impinge on the c-spine or vertebral arteries)
What are the signs and symptoms of atlantoaxial subluxation?
- Headache
- Neck pain
- Extremity paresthesias (especially with movement)
- Bowel/bladder dysfunction
What are the signs/symptoms of vertebral artery occlusion?
- N/V
- Dysphagia
- Blurred Vision
- Transient LOC changes
What ocular syndrome is typical of RA patients?
Sjogren’s syndrome
(Dry eyes and mouth)
What pulmonary issues are associated with RA?
- Interstitial fibrosis
- Restricted ventilation
What type of ventilatory settings would be utilized for an RA patient exhibiting a restrictive ventilatory pattern?
Pressure Control @ 5mL/kg
What artery is typically injured due to pelvic fractures? Where is the bleeding located in this instance?
Iliac artery → retroperitoneal space bleeding
What is the typical worst complication of long bone fractures?
Bone marrow fat embolism
What technique is used for intubation of a patient who has c-spine concerns?
MILS
Manual In-Line Stabilization
Describe the MILS technique
What is the mechanism of action of warfarin?
Warfarin inhibits Vitamin K epoxide reductase and limits the availability of Vitamin K throughout the body
What is the mechanism of action of LMWH?
LMWH binds to antithrombin thus → no thrombin → no fibrinogen forming into fibrin
What are some typical triggers for delirium?
- Hypoxemia
- Hypotension
- Hypercarbia
- Sleep Deprivation
- Hypervolemia
- Infection
- Electrolyte abnormalities
- Pain
- Benzos
- Anticholinergics
- Circadian Rhythm disruption
FEV₁ decreases by ___% for each decade of life.
10%
What occurs with closing volume as we age?
Closing volume increases.
What is the goal of regional anesthesia vs general anesthesia?
Avoid:
- DVT
- PE
- EBL
- Respiratory complications
- Death
With placement of what device is fat embolism syndrome most likely to occur?
Femoral Medullary Canal Rod
What is the s/s Triad of fat embolism syndrome?
When do s/s typically present?
- Dyspnea
- Confusion
- Petechiae
Typically presents in 12 - 72 hrs
What lab findings are noted with fat embolism syndrome?
- Fat macroglobulinemia
- Anemia
- Thrombocytopenia
- ↑ ESR
What is ESR? What are normal values for males and females?
- Erythrocyte Sedimentation Rate
- Male: 0 - 22 mm/hr
- Female: 0 - 29 mm/hr
What minor s/s can be construed to characterize fat embolization syndrome?
- Fever
- ↑HR
- Jaundice
- Renal Changes
What are the anesthetic management techniques for fat embolization syndrome?
Supportive Therapy
- 100% FiO₂
- No N₂O
- IV Heparin
- CV & Resp support
What factors contribute to the development of DVT’s?
- Lack of Prophylaxis
- Obesity
- > 60yrs old
- > 30min procedure
- Tourniquet use
- > 4 days immobilization
- > Lower extremity fracture
Which three surgery types present the greatest risk for DVT formation?
- Hip surgery
- TKA
- Lower extremity trauma
When does LMWH need to be initiated?
12 hours preop
or
12 hours postop
Can neuraxial anesthesia be done after LMWH has been given?
Yes, if 10 - 12 hours after the dose.
Delay next dose 4 hours.
Can an epidural be placed in a patient on LMWH anticoagulation therapy?
No. No indwelling catheters