Orthopaedics Flashcards

1
Q

What causes osteoarthritis?

A

Imbalance between destruction of cartilage and repair by chondrocytes, leading to rubbing together of bones.
RFs: obesity, age, occupation, trauma, female sex and family history.

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2
Q

What is the pattern of joint involvement in OA?

A

Hips
Knees
Sacro-iliac joints
Distal-interphalangeal joints in the hands (DIPs)
The carpometacarpal joint at the base of the thumb (CMC)
Wrist
Cervical spine (cervical spondylosis)

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3
Q

Give 4 x ray changes in OA.

A

L – Loss of joint space
O – Osteophytes (bone spurs)
S – Subarticular sclerosis (increased density of the bone along the joint line)
S – Subchondral cysts (fluid-filled holes in the bone)
severity of symptoms does not correlate with x ray findings.

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4
Q

Give 4 signs in the hands to look for in OA.

A
Heberden’s nodes (in the DIP joints)
Bouchard’s nodes (in the PIP joints)
Squaring at the base of the thumb at the carpometacarpal joint
Weak grip
Reduced range of motion
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5
Q

How is OA diagnosed?

A

Clinical - over 45 years old, pain associated with activity, no morning stiffness >30 mins.

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6
Q

What is the management for OA?

A
Patient education, conservative mx - wt loss, PT, OT, orthotics
Analgesia -
1. PCM+ topical NSAIDs,
2. PO NSAID + PPI, 
3. opiates eg codeine
Topical capsaicin
IA steroid injections
Joint replacement
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7
Q

How would you counsel someone for starting ibuprofen long term?

A
Action - reduce prostaglandins are inflammation
Timeline - mornings, with a PPI
How - PO daily
Length - as long as symptomatic
Effect - a few weeks
Tests - bloods before starting - U+Es 
Important SEs - GI eg gastritis and ulcers leading to bleed, renal - ATN, AKI, CKD; CVD - htn, HF, MI, stroke; exacerbating asthma
CI - asthma, AKI
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8
Q

Give 3 reasons for joint replacement.

A
OA (most common)
RA
Septic arthritis
Fracture
Osteonecrosis
Bone tumours
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9
Q

What is a hemiathroplasty?

A

Replacing half of the joint (eg head of femur in hip joint, this is done in patients who are not medically fit for TJR)

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10
Q

What is partial joint resurfacing?

A

Replacing part of the joint surfaces (eg only the medial joint surfaces of the knee)

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11
Q

How would you explain a total hip replacement to a patient?

A

We make a cut over the outside of the hip. The hip joint is dislocated (separated). The top of the femur, the long bone from the hip to the knee, is removed. A metal or ceramic replacement head of femur, on a metal stem, is used to replace it. The stem can either be cemented into the bone or carefully pushed into the shaft to make a tight enough fit to hold it securely in place. Uncemented stems have a rough surface that holds them tightly in place.

The socket of the pelvis is hollowed out and replaced by a metal socket, which is cemented or screwed into place. A spacer is used between the new head and socket to complete the new artificial joint.

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12
Q

Explain a total knee replacement.

A

Usually, a vertical, anterior incision is made down the front of the knee. The patella is rotated out of the way to allow access to the knee joint.

The articular surfaces (the cartilage and some of the bone) of the femur and tibia are removed. A new metal surface replaces these. They can be either cemented or pushed tightly into place.

A spacer is added between the new articular surfaces of the femur and tibia to complete the new artificial joint.

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13
Q

Explain a total shoulder replacement.

A

Usually, an anterior incision is made down the front of the shoulder, along the deltoid. The shoulder joint is dislocated (separated) to give access to both articular surfaces.

The head of the humerus is removed and replaced with a metal or ceramic ball. This replacement head is attached to the humerus either by a metal stem or screws (stemless).

The glenoid (socket) is hollowed out and replaced by a metal socket. This completes the artificial shoulder joint.

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14
Q

What is a reverse total shoulder replacement?

A

A reverse total shoulder replacement involves adding a sphere in place of the glenoid (socket) and a spacer with a cup to replace the head of the humerus. This reverses the normal ball-in-cup structure of the shoulder joint, but the joint function remains the same.

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15
Q

Give 5 things that are done before joint replacement surgery.

A

X-rays
CT or MRI scans may be required for a more detailed assessment
Pre-operative assessment (pre-op)
Consent for surgery
Bloods (including group and save and crossmatching of blood)
Medication changes if needed (e.g., temporarily stopping anticoagulation)
Venous thromboembolism assessment
Fasting immediately before surgery
The limb will be marked with the patient awake to ensure the operation is performed on the correct joint

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16
Q

What medications are usually given during joint replacement surgery?

A

General anaesthetic. Spinal anaesthetic may be used for lower limb surgery.

Prophylactic antibiotics are given before the procedure to reduce the risk of infection.

Tranexamic acid may be used to minimise blood loss during the procedure.

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17
Q

Give 5 things that are done after joint replacement surgery.

A

Analgesia
Physiotherapy to guide when and how to mobilise
VTE prophylaxis - LMWH 28 days post hip, 14 days post knee
Post-operative x-rays
Post-operative full blood count (to check for anaemia)
Monitoring for complications (e.g., deep vein thrombosis or infection)

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18
Q

Give 5 risks of joint replacement surgery.

A

Risks of the anaesthetic
Pain
Bleeding
Infection of the prosthesis - 1%. Usually staph aureus. RFs - prolonged op time, obesity and diabetes. Symptoms - fever + painful hot red swollen joint. Need to go back to surgery and have prolonged abx.
Damage to nearby structures (e.g., nerves or arteries)
Stiffness or restricted range of motion in the joint
Joint dislocation
Loosening
Fracture during the procedure
Venous thromboembolism (DVT or PE)

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19
Q

What is a compound fracture?

A

Skin is broken and broken bone is exposure to air.

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20
Q

What is a stable fracture?

A

Sections of bone remain in alignment at the fracture site.

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21
Q

What is a pathological fracture?

A

A fracture due to an abnormality in the bone eg lytic lesion.

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22
Q

What is a comminuted fracture?

A

Bone breaks into multiple fragments. Eg butterfly fracture

23
Q

What is a compression fracture?

A

Fracture of spinal vertebrae.

24
Q

What is a greenstick fracture?

A

Fracture only on one side of the bone, doesn’t go fully through. Only in children.

25
Q

What is a Buckle fracture?

A

Aka torus fracture - fractures on either side of bone crash into each other.

26
Q

What is a Salter-Harris fracture?

A

A fracture of the growth plates (only in children)

27
Q

What is a Colle’s fracture?

A

Transverse fracture of distal radius near the wrist, causing the distal portion to displace posteriorly (upwards), causing a ‘dinner fork deformity’. Usually cased by FOOSH

28
Q

Which fracture is usually affected by a FOOSH other than Colle’s?

A

Scaphoid. Causes anatomical snuffbox tenderness. Has retrograde blood supply meaning fracture can cutoff blood supply resulting in avasc necrosis and non-union.

29
Q

Which joints are susceptible to avascular necrosis?

A

Scaphoid bone, the femoral head, the humeral head and the talus, navicular and fifth metatarsal in the foot.

30
Q

What is the Weber classification?

A

Classification of fractures of the lateral malleolus (distal fibula) in the ankle.
Tibiofibular syndesmosis is very important for the stability and function of the ankle joint. If the fracture disrupts the syndesmosis, surgery is more likely to be required in order to regain good stability and function of the joint.
Type A – below the ankle joint – will leave the syndesmosis intact
Type B – at the level of the ankle joint – the syndesmosis will be intact or partially torn
Type C – above the ankle joint – the syndesmosis will be disrupted

31
Q

Which cancers commonly metastasise to bones?

A
Breast
Bronchi (Lung)
Prostate
Kidney
Thyroid
32
Q

What is a pelvic ring fracture and what is the key complication?

A

The pelvis forms a ring. When one part of the pelvic ring fractures, another part will also fracture (similar to fracturing a polo mint).
Pelvic fractures often lead to significant intra-abdominal bleeding, either due to vascular injury or from the cancellous bone of the pelvis. This can lead to shock and death, so needs emergency resuscitation and trauma management.

33
Q

What is a fragility fracture?

A

Occur due to weakness in the bone, usually due to osteoporosis. They often occur without the appropriate trauma that is typically required to break a bone. For example, a patient may present with a fractured femur after a minor fall.

34
Q

How do you calculate risk of fragility fracture over the next 10 years?

A

FRAX.

35
Q

How do you investigate and diagnosed osteoporosis?

A

DEXA scan measures BMD. Generates a T score.
The WHO criteria:
More than -1= Normal
-1 to -2.5 = Osteopenia
Less than -2.5 = Osteoporosis
Less than -2.5 plus a fracture = Severe Osteoporosis

36
Q

How would you counsel a patient for starting bisphosphonates?

A

Action - interfere with osteoclast activity to prevent reabsorption of bone.
Timeline - take once a week
How - tablet with full glass of water, >30 mins before food/drinks, upright for 30 mins after.
Length - long term
Effect - gradual?
Tests -dental check ups before starting then regularly (ONJ)
Important SEs - Reflux and oesophageal erosions, Diarrhoea, constipation, block stools abdo pain
Complications:
Atypical fractures (e.g. atypical femoral fractures)
Osteonecrosis of the jaw
Osteonecrosis of the external auditory canal
CI: pregnancy, dysphagia, stomach ulcers, severe renal impairment.
Supplementary - NOS.org.uk

37
Q

What are the aims of management of a fracture?

A
1. Achieve mechanical alignment of the fracture by either closed reduction via manipulation of the limb or
open reduction via surgery
2. Provide relative stability for some time to allow healing to occur. This can be done by fixing the bone in the correct position while it heals. There are various ways the bone can be fixed in position:
External casts (e.g., plaster cast)
K wires
Intramedullary wires
Intramedullary nails
Screws
Plate and screws
38
Q

How do you manage fractures?

A

X ray
Analgesia
Simple fractures eg Colle’s can be managed in A and E with closed reduction, plaster cast and follow up in fracture clinic.
Complex fractures/those requiring surgery referred to T+O, NBM, trauma meeting the following morning.

39
Q

Give 4 early complications of fractures.

A

Damage to local structures (e.g., tendons, muscles, arteries, nerves, skin and lung)
Haemorrhage leading to shock and potentially death
Compartment syndrome
Fat embolism
Venous thromboembolism (DVTs and PEs) due to immobility

40
Q

Give 4 long term complications of fractures.

A
Delayed union (slow healing)
Malunion (misaligned healing)
Non-union (failure to heal)
Avascular necrosis (death of the bone)
Infection (osteomyelitis)
Joint instability
Joint stiffness
Contractures (tightening of the soft tissues)
Arthritis
Chronic pain
Complex regional pain syndrome
41
Q

What is a fat embolism?

A

Fat embolism can occur following the fracture of long bones (e.g., femur). Fat globules are released into the circulation following a fracture (possibly from the bone marrow). These globules may become lodged in blood vessels (e.g., pulmonary arteries) and cause blood flow obstruction. Fat embolisation can cause a systemic inflammatory response, resulting in fat embolism syndrome.

It typically presents around 24-72 hours after the fracture. Risk lower if you operate early to fix the fracture.

42
Q

How is a fat embolism diagnosed?

A

Gurd’s major criteria:
Respiratory distress
Petechial rash
Cerebral involvement

Gurd’s minor criteria include:
Jaundice
Thrombocytopenia
Fever
Tachycardia
43
Q

What is the management and prognosis of fat embolism syndrome?

A

It can lead to multiple organ failure. Management is supportive while the condition improves. The mortality rate is around 10%.

44
Q

How are hip fractures classified?

A

Intra-capsular - proximal to intertrochanteric line.
- Garden classification:
I incomplete, non-displaced
II complete, non-displaced
III partial displacement
IV full displacement
Extra-capsular:
Intertrochanteric (between greater and lesser trochanter)
Subtrochanteric (distal to lesser trochanter)

45
Q

Describe the blood supply to the femoral head.

A

The capsule of the hip joint surrounds the neck and head of the femur.
The head of the femur has a retrograde blood supply. The medial and lateral circumflex femoral arteries join the femoral neck just proximal to the intertrochanteric line. Branches of this artery run along the surface of the femoral neck, within the capsule, towards the femoral head. They provide the only blood supply to the femoral head. –> risk avasc necrosis.

46
Q

What are the types of intracapsular fracture? How is it managed?

A

Always needs replacement or hemiarthroplasty due to risk of avasc necrosis.
I: incomplete and non-displaced - intact blood supply to femoral head so can be treated with internal fixation only to hold femoral head in place while it heals.
II: complete and non-displaced
III: partially displaced - blood supply to head of femur is disrupted, trabeculae are at an angle.
IV: fully displaced - trabeculae are parallel.

47
Q

How is an extracapsular fracture managed?

A

Do not need replacement as the blood supply is not threatened.
Intertrochanteric - between greater and lesser trochanter, treated with dynamic hip screw aka sliding hip screw.
Subtrochanteric - distal to lesser trochanter in proximal shaft of femur, treated with intramedullary nail.

48
Q

How do hip fractures present?

A

Older patients, fall, pain in groin or hip, radiate to knee, not able to weight bear.
Shortened, abducted and externally rotated leg.

49
Q

What is Shenton’s line?

A

Continuous curving line formed by medial border of femoral neck and continues to inferior border of superior pubic ramus. Seen on AP x ray. Disruption = NOF#.

50
Q

How are hip fractures managed?

A

Appropriate analgesia
Investigations to establish the diagnosis (e.g., x-rays)
Venous thromboembolism risk assessment and prophylaxis (e.g., low molecular weight heparin)
Pre-operative assessment (including bloods and an ECG) to ensure they are fit and optimised for surgery
Orthogeriatrics input
Surgery within 48 hours of admission, should be able to weight bear straight away, OT, PT and analgesia to support mobilisation and rehab asap.

51
Q

What is cauda equina syndrome?

A

Surgical emergency where nerve roots of the cauda equina are compressed.
Cauda equina = nerve roots that travel through spinal canal after spinal cord terminated around L2/3 (conus medullaris).
They supply sensation to perineum, bladder and rectum, motor to lower limbs and anal and urethral sphinters, and parasympathetic to bladder and rectum.

52
Q

Give 5 causes of cauda equina syndrome.

A
Herniated disc (the most common cause)
Tumours, particularly metastasis
Spondylolisthesis (anterior displacement of a vertebra out of line with the one below)
Abscess (infection)
Trauma
53
Q

Give 6 signs and symptoms of cauda equina syndrome.

A

Saddle anaesthesia (loss of sensation in the perineum – around the genitals and anus)
Loss of sensation in the bladder and rectum (not knowing when they are full)
Urinary retention or incontinence
Faecal incontinence
Bilateral sciatica
Bilateral or severe motor weakness in the legs
Reduced anal tone on PR examination

54
Q

What is the difference between cauda equina syndrome and metastatic spinal cord compression?

A

Cauda equina compresses the nerves after they leave the spinal cord - so lower motor neurone (reduced tone and reflexes). MSCC occurs higher up, compressing the actual spinal cord, so you get upper motor neuron symptoms/signs eg increased tone, hyperreflexia and upgoing plantars.