Orthomyxoviridae Flashcards
1
Q
- rod-shaped spikes which attach to sialic acid;
- 16 HA antigens
A
Hemagglutinin (HA)
2
Q
- mushroom-shaped spikes which releases mature virions from infected host cells;
- 9 NA antigens.
A
Neuraminidase (NA)
3
Q
- major genetic changes resulting to novel viral antigens;
- only Influenza A
A
Antigenic shift
4
Q
H1N1
A
Spanish flu
5
Q
H2N2
A
Asian flu
6
Q
H3N2
A
Hongkong flu
7
Q
Asian Avian flu (Highly pathogenic Avian Influenza)
A
H5N1
8
Q
Asian (first reported in China)
A
H7N9
9
Q
o Minor genetic changes that occur infrequently; occurs in all influenza types (A, B, C)
o Annual vaccination
A
Antigenic drift
10
Q
Measles – Koplik’s spots in oral mucosa
A
Rubeola virus/measles
11
Q
Subacute sclerosing panencephalitis
A
Rubula/mumps
12
Q
PIV-1: croup (laryngotracheobronchitis)
PIV-3: bronchiolitis & pneumonia
A
Parainfluenza virus
13
Q
Most significant cause of acute lower respiratory tract infx in children <5 y.o.
A
Respiratory Syncytial virus
14
Q
Picornaviridae
A
refer to handout page 6
15
Q
Major cause of common cold
A
Rhinovirus (acid- sensitive)
