Laboratory Diagnosis for Viruses Flashcards
1
Q
Most rapid method of diagnosis for non- culturable viruses (hepatitis virus, norwalk virus)
A
Electron Microscope
2
Q
Detection of cytoplasmic inclusions/cytopathic effects
A
Light Microscopy
3
Q
Negri Bodies
A
rabies
4
Q
Torres Councilman Bodies
A
Yellow fever
5
Q
Cowdry Type A
A
- HSV Herpes Simplex Virus
- VZV Varicella Zoster Virus
(Tzanck smear)
6
Q
Owl’s eyes
A
CMV
7
Q
Koilocytes
A
HPV (Pap smear)
8
Q
Henderson-Patterson Bodies
A
Molluscum contagiosum (poxyviridae)
9
Q
Guarnieri bodies
A
Pox Virus
10
Q
For detection of HPV carcinoma
A
Pap Smear
11
Q
For HSV & VZV; multinucleated giant cell
A
Tzanck smear
12
Q
- obtained from animals
- Primary Monkey Kidney
- Human Embryonic Kidney
- Rhesus Kidney
A
Primary Cell Culture
13
Q
- subcultivated primary culture
- MRC-5, WI-38,
- Human Diploid Fibroblast (HDF)
A
Diploid Cell Culture
14
Q
- immortal cell lines
- cancer cells
- HeLa, Hep2, A-549, AGMK
A
Continuous Cell Culture
15
Q
detects blockade of cytopathic effects Complement fixation
A
Neutralization
16
Q
for influenza and rubella
A
Hemagglutination inhibition
17
Q
- Presence of viral DNA or RNA is the gold standard in viral diagnosis
A
Nucleic acid detection
18
Q
DNA Viruses
A
refer to handout page 5
19
Q
RNA Viruses
A
refer to handout page 5-6
