Ortho/Rheum Flashcards
What is the treatment for dry eyes from Sjögren’s?
Cyclosporine
What condition is most commonly seen with Raynauds?
Scleroderma
Anti-Ro and Anti-la antibodies?
Sjögren’s
What condition does a Schirmer test help diagnose?
Sjögren’s
What condition is associated with CREST syndrome?
Scleroderma
Anticentromere antibody?
Scleroderma
What is the Dx? 20 year old female with pericarditis and rash.
Systemic lupus erythematosus (SLE)
Anti-smith antibodies?
Systemic lupus erythematosus (SLE)
List the causes of Reiters syndrome.
Chlamydia - Salmonella - Clostridium difficile - Campylobacter jejuni
Uveitis urethritis and oligoarthritis?
Reiter’s syndrome
What disease is associated with polymyalgia rheumatica?
Giant cell arteritis
What is the Dx? AM Stiffness in shoulders and hip girdle in a 50 year old.
Polymyalgia Rheumatica
Anti jo1 antibodies?
Polymyositis
What treatment is used for acute pseudogout?
Steroids and aspiration of the joint
What medications are used for acute gout?
Colchicine and indomethacin
What medication is used for chronic gout?
Allopurinol
Most common part of body to get a pseudogout attack?
Knee
Most common part of body to get a gout attack?
First MTP joint (AKA: Podagra)
Positive birefringent crystals?
Pseudo gout
Negative birefringent crystals?
Gout
How many fibromyalgia trigger points are needed for diagnosis?
Greater than 11 of 18
Fibromyalgia treatment?
Tricyclics (e.g. amitriptyline) - Patient education
Osteoporosis treatment?
First line: bisphosphonates consider denosumab - teriparatide
Swan neck deformity and ulnar deviationn associated with?
Rheumatoid arthritis
Boutonniere deformity associated with?
Rheumatoid arthritis
Bouchard nodes associated with?
Osteoarthritis
Heberden’s nodes associated with?
Osteoarthritis
What medication is often used to treat the pain and inflammation of Sjögren’s syndrome?
Hydroxychloroquine with steroids for the pain and inflammation
What antibodies are associated with Sjögren’s syndrome?
Anti-Ro and anti-La antibodies also known as SSA and SSB
What are two common complications associated with Sjögren’s syndrome?
Primary biliary cirrhosis and non-Hodgkin’s lymphoma
Which antibody is associated with scleroderma?
Anti-centromere antibody
Will a patient with scleroderma develop dysphagia to solids, liquids, or both liquids and solids?
Both liquids and solids
Patients with SLE are commonly treated with what two types of medications?
Corticosteroids and immune modulation medications like cyclophosphamide
Screening for SLE is performed using the ANA antibody. Which antibody is confirms the diagnosis?
Anti-Smith antibody
A 30 year old female presents with erythema over the cheeks and nose and pericarditis. What do you suspect?
Systemic lupus erythematosus
Which rheumatologic disorder may follow infection with Chlamydia, Campylobacter Jejuni or Clostridium difficile?
All three infections can lead to Reiter’s syndrome (also known as reactive arthritis)
What condition do you suspect in a 54 year old with stiffness specifically in the shoulders and hip girdle?
Polymyalgia rheumatica
How does polymyositis differ from myasthenia gravis?
Polymyositis does not cause facial or ocular weakness like that which is seen in myasthenia gravis
What is the diagnostic test of choice in a patient with dermatomyositis?
Muscle biopsy
A 50 year old man has a purplish mottled discoloration of the torso, muscle pain, extremity weakness, weight loss and HTN. What condition do you suspect?
Polyarteritis nodosa
What is the age of onset for psoriatic arthritis?
Between the ages of 30 to 50 (Skin involvement occurs before the joint involvement)
What is the age cut off for someone to have juvenile rheumatoid arthritis?
Joint stiffness for more than six weeks in a child 16 or younger
Name three deformities seen in rheumatoid arthritis.
Ulnar deviation - Swan neck deformity - Boutonniere deformity
Which bone cancer is most likely to start in the spine or pelvis of children?
Ewings sarcoma
What age group is osteosarcoma most likely to affect?
Second decade of life
What is the Dx? Patient in his 20s with progressive bone pain worse at night and a sunburst appearance on X-ray.
Osteosarcoma
What is the most common bone location for metastasis of other (non-ortho) cancers?
Spine
Which type of bone cancer is usually seen in patients over 50 years of age?
Chondrosarcoma
Name 3 types of Bone cancer.
Osteosarcoma - Chondrosarcoma - Ewings sarcoma
What pathogen can cause septic arthritis in healthy sexually active young adults?
Neisseria gonorrhoeae
Treatment for osteomyelitis?
Debridement - Blood and wound cultures - Antibiotics based on culture for 6 + weeks - Remove hardware if present