GI Flashcards
What are the three borders of Hesselbach’s triangle?
Medial border: rectus abdominus - Superior border: inferior epigastric artery - Lateral border: inguinal ligament
What is the most common cause of painless rectal bleeding in pediatric population?
Polyps
What is intestinal pseudo-obstruction without evidence of mechanical cause called?
Ogilvie Syndrome
List the 6 “rule of 2” characteristics of Meckel’s diverticulum.
2% of population - 2 feet proximal to ileocecal valve - 2 inches long - 2 years old - 2:1 M:F ratio - 2 tissues: gastric & pancreatic
Slate colored skin may represent which underlying GI disorder?
Primary Biliary Cirrhosis
What agent is used to chelate copper in the treatment of Wilson’s disease?
Penicillamine
Treatment of chronic hepatitis due to hemochromatosis?
Phlebotomy and deferoxamine chelation
Treatment of chronic hepatitis due to Wilson’s disease?
Copper chelation
Treatment of chronic autoimmune hepatitis?
Corticosteroids
Treatment of chronic viral hepatitis B or C?
Pegylated interferon-alpha
What serum gastrin levels are found with Zollinger Ellison Syndrome?
> 150 pg/mL is suggestive - > 200 pg/mL is diagnostic
What level of eosinophilia is diagnostic of eosinophilic esophagitis on biopsy?
> 15 eosinophils/HPF
What type of diarrhea is seen in patients with cholera?
Secretory diarrhea
What type of diarrhea does lactose intolerance often cause?
Osmotic diarrhea
What type of infectious diarrhea is often linked to deli meats and can be deleterious in pregnant woman (lead to miscarriage)?
Listeria
Which vitamin deficiency can lead to problems clotting and excessive bleeding?
Vitamin K
Patient with Hepatitis C is at high risk for which malignancy?
Liver cancer
What disease is caused by vitamin C deficiency?
Scurvy
What disease is caused by niacin deficiency?
Pellagra
What vitamin deficiency can lead to cause rickets in children?
Vitamin D
Name the fat soluble vitamins.
Vitamins: ADEK
Congenital error of metabolism in which life-long avoidance of phenylalanine is required?
Phenylketonuria
What is the Dx? Nursing home patient with severe watery diarrhea after recent antibiotics.
C. difficile
Prophylactic antibiotic given to prevent traveler’s diarrhea?
Fluoroquinolone (e.g. ciprofloxacin) - (Pregnant woman or child give azithromycin)
Which disorder commonly has cobblestoning or skip lesions on imaging?
Chron’s
What test is used to diagnose lactase deficiency?
Lactose breath hydrogen test
Which vitamin deficiency is perifollicular petechiae suggestive of?
Vitamin C (Scurvy)
What diarrhea related infection may lead to meningitis in neonates and immunocompromised patients?
Listeria
What type of inguinal hernia is felt on the side of the finger during exam?
Direct
What type of inguinal hernia is felt on the tip of the finger during exam?
Indirect
Treatment for Giardia infection?
Metronidazole
Does Shigella cause bloody or non-bloody diarrhea?
Bloody diarrhea
Will umbilical hernias in children <12 months old usually resolve on their own?
Yes
Risk factors for ventral hernia?
Abdominal surgery - Age - Obesity - Wound infection - Surgical drains
What is the Dx and treatment? Stomach herniated up into thorax.
Paraesophageal hernia - Surgery recommended
Common symptoms associated with sliding hiatal hernia?
Reflux and heartburn
Patient with adenomatous colon polyp should have colonoscopy how often?
Every 3-5 years
Rectal mass rectal bleeding and tenesmus?
Rectal cancer (solitary tenesmus may occur with anal inflammation)
What type of hemorrhoids are usually painless?
Internal hemorrhoids
Tender indurated area at perianal area/gluteal cleft?
Pilonidal Cyst
What disorder is colon dilation air fluid levels and thumbprinting sign on imaging suggestive of?
Toxic megacolon (Thumbprinting may also occur with mesenteric ischemia)
Treatment for fecal impaction?
Digital rectal /manual disimpaction - Diet with fiber stool softeners/laxatives for prevention
What is the Dx? Acute abdominal pain. KUB shows dilated loops of bowel with air fluid levels.
Small bowel obstruction
Name the 3 most common symptoms of pellagra.
“Diarrhea - Dementia - Dermatitis (3 “D”s)
At what age should routine colonoscopy screening begin for men and women?
Age 50
Most common type of colon cancer?
Adenocarcinoma
What is the DX? 65-year-old male 3 months of recent weight loss poor appetite new constipation and anemia.
Think colon cancer
Celiac sprue intestinal biopsy findings?
Villous atrophy
Good test for malabsorption?
Fecal fat testing
Steatorrhea is often associated with which type of bowel disorders?
Malabsorption disorders
Intestinal angina?
Chronic mesenteric ischemia
What is the Dx? 60-year-old male smoker complains of recurrent dull abdominal cramps/pain within 1 hour of eating meals.
Chronic mesenteric ischemia
What is severe abdominal pain out of proportion to physical exam findings suggestive of?
Acute mesenteric ischemia
Acute thrombosis or embolism of the celiac or mesenteric arteries?
Acute mesenteric ischemia
Name the criteria used to diagnose Irritable bowel syndrome.
Rome criteria: Pain relieved with defecation - Change in frequency and form - Altered stool passage - Passage of mucus
Inflammatory bowel disease that may affect the entire GI tract from mouth to anus?
Chron’s
What are the extraintestinal manifestations that can be seen in ulcerative colitis patients?
Pyoderma gangrenosum - Arthritis - Ankylosing spondylitis - Erythema nodosum - Uveitis
Inflammatory bowel disease that only affects the large intestines?
Ulcerative colitis
Inflammatory bowel disease that often presents with bloody diarrhea?
Ulcerative colitis
What is the Dx? Newborn with double bubble sign on abdominal X-ray.
Duodenal atresia
List 3 antibiotic regimens which can be used for diverticulitis?
Quinolone with metronidazole - Amoxicillin-clavulanate - Trimethoprim-sulfamethoxazole
Treatment for acute diverticulitis?
Initial: NPO/IV fluids antibiotics - May require surgery if perforation or abscess
+anti-tissue transglutaminase +antigliadin and +anti endomysial antibodies are suggestive of what disorder?
Celiac sprue
What cardiac disorders are acute mesenteric ischemia associated with?
Atrial fibrillation - MI - CHF
What genetic abnormality is duodenal atresia associated with?
Hereditary Spherocytosis
What criteria are used to predict mortality in acute pancreatitis?
Ranson’s criteria
What chronic viral diseases increases the chance of liver cancer?
Hepatitis B and C (C increases chances more than B)
What tumor marker may be elevated in liver cancer?
Alpha-fetoprotein
Common causes of constipation?
Lack of fiber - Opiate use - hypothyroidism
Sign seen with appendicitis with pain over the right lower quadrant one-third of the distance from the ASIS to the umbilicus?
McBurney’s
Tumor marker elevated with pancreatic cancer?
CA 19-9
Most common type of pancreatic cancer?
Ductal adenocarcinoma
Ecchymoses around the umbilicus which represents retroperitoneal or intra-abdominal bleeding?
Cullen’s sign
What is the Dx? Epigastric pain radiating to back with elevated lipase.
Acute Pancreatitis
What does a porcelain gallbladder or a radiopaque gallbladder on imaging suggest?
Gallbladder cancer
What disease process does Charcot’s triad (fever, jaundice and RUQ pain) suggest?
Cholangitis
What are the routes of transmission for hepatitis C?
Infants: perinatal infection Adults: Blood to blood exposure - Sexual - IV drug abuse - tattoos
What are the routes of transmission for hepatitis B?
Infants: perinatal infection Adults: Blood to blood exposure - Sexual - IV drug abuse
What are the routes of transmission for hepatitis A?
Fecal-oral
Which types of hepatitis have available vaccines?
Hepatitis A and B
Non-alcoholic steatohepatitis (AKA non-alcoholic fatty liver disease) risk factors?
Diabetes obesity - Metabolic syndrome - Steroid use - CAD
What are +Anti-Mitochondrial antibodies associated with?
Primary Biliary Cirrhosis
What is the Dx? Fatigue Pruritus hepatomegaly associated with high alk phos cholesterol and bilirubin.
Primary Biliary Cirrhosis
Treatment for acetaminophen toxicity?
Acetylcysteine
Treatment for Wilson’s disease?
Copper chelation
Most common type of Hepatitis which is transferred via fecal-oral route?
Hepatitis A
What findings are expected in a patient who is immune to Hepatitis B due to vaccination?
HBsAg negative - Anti-HBc negative - Anti-HBs positive
What findings are expected in a patient who is immune to Hepatitis B due to natural infection?
HBsAg negative - Anti-HBc IgG positive - Anti-HBs positive
RUQ palpation maneuver reveals pain and cessation of inspiration. What is this called? What does it indicate?
Murphy’s sign = cholecystitis
Most common type of gastric cancer?
Gastric adenocarcinoma
Medications to treat gastroparesis?
Metoclopramide - IV erythromycin
Treatment for gastritis?
Proton pump inhibitor - Treat H. Pylori if present - Remove irritants
List two medications which may cause cholelithiasis?
Ceftriaxone and Clofibrate
What two hematological disorders may cause cholelithiasis?
Sickle cell disease and Hereditary spherocytosis
What GI cancer is acanthosis nigricans associated with?
Gastric adenocarcinoma