Ortho - CL(P) Flashcards
At what stage in utero does the palate begin to form?
6-10 weeks
where are the palatal shelves formed from?
the 2 maxillary prominences
what pharyngeal arch are the palatal shelves/maxillary prominences formed from?
1st
what forms the primitive premaxilla/the primary palate?
the inferior extension of the of the medial nasal processes
what forms the secondary palate?
the 2 palatal shelves from the maxillary processes
at what week in utero does the primary ad secondary palates fuse?
week 9
- by week 10 the nasal cavity and oral cavity are separate
What causes cleft lip?
failure of the maxillary prominence to fuse with the medial nasal process
on what side and i what sex is cleft lip most commonly found?
LHS
MALE - 3 males: 1 female
What causes cleft palate?
failure of the 2 palatal shelves to fuse In the midline
What sex is most likely to have cleft lip in isolation and why?
Isolated cleft palate more common in females this is suggested to be caused by the later elevation of the palatal shelf (M = week 7, F = week 8)
How do we classify Cleft lip and palate?
Describe how this classification system is used.
LAHSHAL classification:
Designate a letter for every structure the cleft goes through;
L = lip
A =alveolus
H = hard palate
S = Soft palate
Small letter instead of capital = not complete deformity
What percentage of clefts lip and palates are unilateral?
What percentage of clefts lip and palates are bilateral?
80% - unilateral
20% bilateral
How common is CL(P)?
1:700 live births
What is the main cause of CL(P)?
70% sporadic
List genetic causes of CL(P). (5)
- Syndromes
- Family history (if u have a child with a cleft = 5% chance of another child with cleft)
- Sex ration
- Laterality: more common on the left
- Ethnic distribution