OM - Therapeutic Medications Flashcards
What are licensed medications?
A medicine that has been proven in evidence to the MHRA to have efficacy and safety at defined doses in a child and/or adult population when treating specified medical conditions
Who has responsibility for the safety of licensed medication use?
the manufacturer
What are unlicensed medications?
Medicines that have not had evidence of efficacy submitted to the MRHA for the condition under treatment
(doesn’t mean that the drug has no efficacy just means that the efficacy has not been proven to MRHA)
- Unlicenced meds shouldn’t be used if there is a licensed option available – not often the case in mucosal diseases in OM.
Who has responsibility for the safety of unlicensed medication use?
The prescriber
What must the prescriber provide alongside an unlicensed medicine?
PIL (safety measures and instructions) specifically for its use to treat the unlicensed condition - cannot use the one provided by the manufacturer
What LICENSED medications are used to treat oral medicine conditions? (4)
- Anti-microbials
- Anti-viral
- Anti-fungal
- Antibiotics
- Benzdamine mouthwash
- Carbamazepine (trigeminal neuralgia)
- Dry mouth medication – medical devices
What medications are unlicensed for use in treating oral medicine conditions however are still used?
- Topical Steroids
- Inhaled steroids
- Steroid mouthwash
What are antivirals e.g. Acyclovir used to treat in OM? (3)
- primary herpetic gingivostomatitis
- recurrent herpetic lesions
- shingles (recurrent herpes zoster)
Name examples of antifungals used in OM. (3)
Miconazole, Fluconazole, Nystatin
What are antifungals used to treat in OM? (2)
Acute pseudomembranous candidiasis
acute erythematous candidiasis
What are topical steroids used to treat in OM? (2)
- aphthous ulcers
- Lichen planus
Name examples of topical steroids used in OM. (2)
Betamethasone mouthwash (soluble tablets to make a mouthwash)
Beclomethasone Metered Dose Inhaler
What are medical devices? Provide a relevant example to OM.
Any instrument, apparatus, implement, machine, appliance, implant, reagent for in vitro use, software, material or other similar or related article, intended by the manufacturer to be used, alone or in combination, for human beings, for one or more of the specific medical purpose(s) and does not achieve its primary intended action by pharmacological, immunological or metabolic means, in or on the human body, but which may be assisted in its intended function by such means.
e.g. dry mouth treatments – used to replace saliva (not a pharmacological input but a lubricant impute)
List dry mouth treatments regarded as medical devices (5)
- Salivix pastilles
- Saliva orthana
- Biotene Oral Balance
- Artificial Saliva DPF
- Glandosane
List more advanced drugs used in OM and examples of what they are used for. (6)
- Tricyclic Antidepressants
- Gabapentin/Pregabalin (management of chronic pain)
- Azathioprine (immunosuppression for lichen planus, apthus ulcers etc )
- Mycophenolate (immunosuppression for lichen planus, apthus ulcers etc)
- Hydroxycholoroquine (used for lichen planus, apthus ulcers)
- Colchicine (used for lichen planus, apthus ulcers)