ORS Powder

Question 1

mixture of finely divided drugs and/ or chemicals in a dry form

Answer 1

powders

Question 2

may be used to describe the PHYSICAL FORM of a material that is DRY SUBSTANCE composed of FINELY DIVIDED powders

Answer 2

powders

Question 3

may use to describe a type of pharmaceutical

Answer 3

powders

Question 4

intended for internal or external use

Answer 4

medicated powder

Question 5

Powders are available in ______________ or ______________ form

Answer 5

crystalline or amorphous

Question 6

Powders were found to be a _________________ mode of administering drugs derived from _________ origin

Answer 6

convenient; plant

Question 7

Most active and inactive pharmaceutical ingredients occur in the solid state as _______________________ or ___________ of various morphologic structures

Answer 7

amorphous powders or crystals

Question 8

a solid dosage form composed of a solid or mixture of solids reduced to
affinely divided state and intended for internal or external use

Answer 8

powders

Question 9

classification of powders according to PARTICLE SIZE

Answer 9

1. very coarse
2. coarse
3. moderately coarse
4. fine
5. very fine

Question 10

classification of powders according to USE or manner of ADMINISTRATION

Answer 10

1. internal
2. external

Question 11

classification of powders according to manner of DISPENSING

Answer 11

1. bulk
2. divided

Question 12

particle size of pharmaceutical powders and granules may range from _________________ in diameter to extremely fine, approaching colloidal dimensions of 1 micrometer or less

Answer 12

10 mm or 1 cm

Question 13

all particles pass through a #8 sieve and NMT 20% pass through a #60 sieve

Answer 13

very coarse

Question 14

all particles pass through a #20 sieve and NMT 40% pass through a #60 sieve

Answer 14

coarse

Question 15

all particles pass through a #40 sieve and NMT 40% pass through a #80 sieve

Answer 15

moderately coarse

Question 16

all particles pass through a #60 sieve and NMT 40% pass through a #100 sieve

Answer 16

fine

Question 17

all particles pass through a #80 sieve. There is no limit
to greater fineness

Answer 17

very fine

Question 18

can be taken orally like ORS and administered through the nose as snaps or blown into a body cavity as insufflations

Answer 18

internal powders

Question 19

dusting powders: medical or surgical

Answer 19

external powders

Question 20

for superficial skin conditions in which shall not be used on open
wounds or broken skin

Answer 20

medical powders

Question 21

sterile and used inside the body cavities

Answer 21

surgical powders

Question 22

locally applied nontoxic preparations with no systemic effect

Answer 22

dusting powders (topical bulk powders)

Question 23

applied as lubricant, protective, absorbent, antiseptic, antipruritic, astringent, antiperspirant

Answer 23

dusting powders (topical bulk powders)

Question 24

used to clean teeth and polish teeth

Answer 24

dentrifices

Question 25

dissolved in water and used as antiseptic or cleansing agent of the body cavity

Answer 25

douche powders

Question 26

also known as undivided powders

Answer 26

bulk powders

Question 27

dusting powders, effervescent antacids, laxatives, dietary nutrients, and supplements

Answer 27

bulk powders

Question 28

examples are drug packets, sachet, capsules

Answer 28

divided powders

Question 29

usually folded in paper dispensed in metal foil, small sealed or reusable plastic valve or container

Answer 29

divided powders

Question 30

requirements in powder manuf

Answer 30

1. homogenous blending 2. reduction into a more advantageous particle size

Question 31

blending techniques

Answer 31

1. spatulation 2. trituration 3. geometric dilution 4. sifting method 5. tumbling

Question 32

blending of SMALL AMOUNT of powder by movement of a pharmaceutical spatula through them on a sheet of paper or ointment tile

Answer 32

spatulation

Question 33

mixture that MELTS AT LOWER TEMPERATURE than any other ingredients when enclosed and prolonged contact with one another

Answer 33

eutectic mixture

Question 34

not suitable for large quantities of powder and not recommended for powders containing potent substances

Answer 34

spatulation

Question 35

provides INTIMATE blending of powders

Answer 35

trituration

Question 36

types of mortar used in trituration

Answer 36

Porcelain, Wedgewood, or glass

Question 37

ROUGH inner surface is preferred than a glass mortar with a smooth working surface

Answer 37

porcelain or ceramic mortar

Question 38

preferred for CHEMICAL THAT STAINS that stains porcelain or ceramic surface as well as for simple admixture of substance without special need for comminution

Answer 38

glass mortar

Question 39

CLEANS READILY after use and trituration is not recommended for eutectic mixtures

Answer 39

glass mortar

Question 40

for MIXING POTENT SUBSTANCES with a large amount of diluent

Answer 40

geometric dilution

Question 41

placed on APPROX EQUAL VOLUME or amount of diluent in a mortar and mixed by trituration

Answer 41

potent drug

Question 42

recommended or indicated on instances in which the potent and non-potent substance are of the same color and visible sign of thorough mixing is lacking

Answer 42

geometric dilution

Question 43

SIMPLEST and probably most COMMONLY used method for mixing powders or particle size determination

Answer 43

sifting method

Question 44

powders are mixed by passing them through sifters like the type used in the kitchen to sift flour

Answer 44

sifting method

Question 45

Sifting results in a ____________________________

Answer 45

light, fluffy product

Question 46

not acceptable for incorporating potent drugs into a diluent base

Answer 46

sifting method

Question 47

tumbling the powder in a rotating chamber

Answer 47

tumbling

Question 48

mixing powder in a large enclosed container, ROTATED by a motorized process

Answer 48

tumbling

Question 49

V-blended and twin shell blender

Answer 49

tumbling instruments

Question 50

study of small particles

Answer 50

micromeritics

Question 51

T/F: It is very important to study particles because MOST drug dosage forms are SOLIDS

Answer 51

True

Question 52

Solids are not ___________ systems

Answer 52

static

Question 53

REDUCING particle size with a FINER state of subdivision

Answer 53

comminution

Question 54

Considerations in Comminution and Blending of powders

Answer 54

1. quantity 2. equipment available

Question 55

particle size determination

Answer 55

1. sieving 2. coulter counter 3. microscopic analysis 4. sedimentation rate 5. light scattering 6. laser diffraction analyzer 7. laser halography

Question 56

good source of Sodium, Potassium and chloride

Answer 56

sodium chloride and potassium chloride

Question 57

helps correct the subsequent metabolic acidosis caused by diarrhea and dehydration

Answer 57

sodium bicarbonate

Question 58

glucose transport is coupled with sodium absorption

Answer 58

anhydrous glucose

Question 59

Electrolytes should be expressed in ______

Answer 59

mEq

Question 60

side effects of ORS

Answer 60

nausea and vomiting