Organogenesis Flashcards

0
Q

Summary: (FIGR)

  1. _________ and the pre-implantation period - formation of the morula and blastocyst
  2. __________
  3. __________ - formation of the three germ layers
  4. __________ of the 3 week old embryo
    a. Head, tail, neural plate, notochord
A
  1. Fertiliztion
  2. Implantation
  3. Gastrulation
  4. Regioinalization
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1
Q

In what period of embryogenesis does organogensis begin?

A

Somite period

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2
Q

If something traumatic or dangerous happens in the first __ weeks of development, you’ll see the development of major congenital anomalies.

A

8 weeks

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3
Q

The notochord induces formation of the _________ ________ (neurulation) in the overlying ectoderm. This then becomes a ________ ________ by active cell proliferation and changes in cell shape.

A

Neural plate –> Neural groove

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4
Q

The neural tube begins closing in the middle and has open ends which are referred to as the ________.

A

neuropores

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5
Q

Which end expands rapidly due to differential growth?

A

anterior

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6
Q

The failure of the posterior neural tube closure.

A

Spina bifida

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7
Q

The failure of anterior neural tube closure.

A

Anencephaly

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8
Q

The failure of the neural tube to close head to tail.

A

Craniorachischisis

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9
Q

Problems with neurulation can be prevented with increase of what in your diet?

A

folic acid

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10
Q

Mesoderm Differentiation:

  • Somatopleural includes _________ and _________.
  • Splanchnopleural includes _________ and __________.
A

Somatopleural (mesoderm and ectoderm)

Splanchnopleural (mesoderm and endoderm)

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11
Q

The paraxial mesoderm becomes _________, which are transient organs that organize themselves without cell differentiation (primary organs). Also referred to as blocks of mesoderm that are located on either side of the neural tube in the developing vertebrate embryo.

A

somites

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12
Q

The segmental (metamere) partitioning of the spine, the neural tube, the trunk wall, and the ribs depend on what?

A

the ordered arrangements of the somites

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13
Q

The somite consists of what three components?

A

dermatome, myotome, and sclerotome

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14
Q

Which component of the somite forms the connective tissue of the dermis?

A

dermatome

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15
Q

Which component of the somite forms muscle?

A

myotome

16
Q

Which component of the somite forms skeletal elements of the vertebral column?

A

sclerotome

17
Q

How many embryonic somites are there?

How many fully formed fetus somites are there?

A

embryonic (42-44)

fetus (35-37)

18
Q

The somite forms from the _________ mesoderm. Early somites have a central cavity and cells are _________-like. Ventral cells lose this characteristic.

A

paraxial, epithelial

19
Q

In summary of neurulation:

  1. We formed the neural plate into a neural ________.
  2. The mesoderm formed _________ and then contributed to the vertebra and muscles.
  3. We now need to ________ the embryo.
A
  1. neural tube
  2. somites
  3. fold
20
Q

Mesodermal Derivatives:

  1. vertebrae, dermis, muscles
  2. urogenital system (ie. kidney)
  3. Lateral Plate Mesoderm
    a. forms somatic lining of the periotonium, muscles of the limbs and body wall
    b. forms muscle of the gut and mesentery
A
  1. Paraxial Mesoderm
  2. Intermediate Mesoderm
  3. Lateral Plate Mesoderm
    a. Somitopleurae
    b. Splanchnopleurae