Organization of the Motor System Flashcards
What are the six parts of the motor system?
- Motor cortex
- Basal ganglia
- Cerebellum
- Brainstem
- Spinal cord
- Motor neurons
Explain the function of the motor system during a hand movement
- Visual system (what part of object should be grasped)
- Information relayed to corticomotor regions (frontal lobe motor regions - plan and initiate movement)
- Instructions sent to spinal cord (muscles of arm and hand receive message from motor neurons)
- Information from fingers travels to spinal cord
- Sent to sensory regions of the cortex that interpret touch (basal ganglia judges grasp forces; cerebellum corrects movement errors)
- Sensory cortex informs motor cortex that object is now being held
What are the four regions in the neocortex used for skilled movement?
- Posterior cortex (specify movement goals and send information to PFC)
- PFC (generates plans for movement)
- Premotor cortex (recognizes movement of other and selects similar or different actions, organizes movement sequences; “lexicon” of movements)
- Primary motor cortex (executes movements)
In what areas of the brain does blood flow increase when a subject uses a finger to press a lever?
- Primary somatosensory cortex
- Primary motor cortex
In what areas of the brain does blood flow increase when a subject performs a sequence of movements?
-Premotor cortex
In what areas of the brain does blood flow increase when a subject use a finger to find a route through a maze?
-Prefrontal, temporal, and parietal cortex
What area of the cortex is the precentral gyrus known as? What is the motor homunculus?
- The primary motor cortex
- Contains motor homunculus (different areas can be stimulated to cause movement in different areas of body)
- Disproportionate in relative sizes of body areas; areas that are larger have more motor control
What is the motor cortex specialized for?
- Control of movements, rather than control of individual muscles
- Movements include: defensive postures of the face, movement of hand to mouth, manipulation and shaping of the hand, outward reach with the hand, climbing and leaping
What is the evidence for a human movement lexicon?
- The pincer grasp (used to reach for small objects, babies begin to spontaneously make the movement)
- When lesions occur to the thumb region of the cortex, weakness appears in all fingers
What are the functions of motor neurons?
- Calculate distance and direction of movement
- Each neuron is maximally responsive to a particular direction
- Activity is decreased in proportion to the displacement from the preferred direction
What are mirror neurons? What function do the serve?
- Neurons that fire when we see others make a movement
- Encode a complete action that can be used for imitating and for understanding others’ actions
- Can “fill in the blanks” when part of movement is absent. Don’t fire when target object is missing
- Can have a broad range of responses
- In humans mirror neurons are typically located in the left hemishpere, they play a role in self-action, perception of action, self-awareness, and awareness of the intention and actions of others. Also important for gestures and verbal movement
Basal ganglia damage causes what kind of disorders?
- Disorders of too much force (Huntington’s chorea and Tourette’s syndrome)
- Disorders of too little force (Parkinson’s disease) Involuntary movements vs. difficulty making movements
What are the two pathways of the basal ganglia? How do they work?
- Excitatory (high excitation (excitatory > inhibitory) in the globus pallidus internal (GPi) which causes a decrease in the force of movements)
- Inhibitory (high inhibition (inhibitory > excitatory) of GPi which causes amplification of movement)
What is the function of the cerebellum?
- Acquiring and maintaining motor skills
- Timing of movements
- Maintain movement accuracy
How is the cerebellum involved in timing of movements? What are the two tests of timing?
- Cerebellum acts like a pacemaker and ensures that both movements and perceptions are appropriately timed
- Motor test of timing - tap a finger in rhythm with a metronome, metronome is turned off, attempt to keep tapping with same beat
- Perceptual test of timing - presented with two pairs of tones, silence between tone in second pair varies in length (longer or shorter than first)
- Patients with damage to cerebellum perform poorly on both tasks