Organic synthesis Flashcards

1
Q

Alkane to Haloalkane

A

X2

UV light

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2
Q

Alkene to Alkane

A

H2
Nickel cat
150°C

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3
Q

Alkene to Haloalkane

A

HX

20°C

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4
Q

Haloalkane to Alcohol

A

Warm KOH/NaOH
H2O
Reflux

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5
Q

Alcohol to Haloalkane

A

NaX
H2SO4
20°C

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6
Q

Alkene to Dihaloalkane

A

X2

20°C

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7
Q

Alkene to Alcohol

A

Steam
300°C
60-70atm
H3PO4 cat

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8
Q

Alcohol to Ester

A
Carboxylic acid
Acid cat
Heat 
OR
Acyl Chloride 
OR
Acid Anhydride
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9
Q

Ester to Alcohol

A

Dilute acid or Alkali

Reflux

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10
Q

Haloalkane to Nitrile

A

NaCN or KCN
Ethanol
Reflux

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11
Q

Haloalkane to Amine

A

Excess ethanolic ammonia

Heat

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12
Q

Nitrile to Amine

A
LiAH4
Dilute acid
OR
H2
Ni cat
High temp and pressure
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13
Q

Alcohol to aldehyde/ketone

A

K2Cr2O7
H2SO4
Distil

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14
Q

Aldehyde/ketone to Alcohol

A

NaBH4

H2O

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15
Q

Hydroxynitrile to Amine

A
LiAlH4
Dilute acid
OR
H2
Ni cat
High temp high pressure
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16
Q

Nitrile to Carboxylic Acid

A

Dilute HCl

Reflux

17
Q

Aldehyde/Ketone to Hydroxynitrile

A

HCN

18
Q

Hydroxynitrile to carboxylic acid

A

Dilute HCl

Reflux

19
Q

Aldehyde/Ketone to Carboxylic Acid

A

K2Cr2O7
H2SO4
Reflux

20
Q

Carboxylic acid to Ester

A

Alcohol
Acid cat
Heat

21
Q

Ester to Carboxylic Acid

A

Dilute acid
OR
alkali
Reflux

22
Q

Acyl chloride to Ester

A

Alcohol

20°C

23
Q

Carboxylic acid to Acyl chloride

A

SOCl2

24
Q

Acyl chloride to Carboxylic acid

A

Cold H2O

25
Q

Acyl chloride to Amide

A
(Primary amide)
NH3
20°C 
Or
(Secondary amide)
Amine 
20°C
26
Q

Alcohol to Alkene

A

Conc acid cat

170°C