Organ Transplantation and Rejection Flashcards by Matthew Cross

Q

Donor and recipient are the same individual

A

Autologous

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Q

Donor and recipient are genetically identical

A

Syngeneic

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Q

Donor and recipient are genetically different but of the same species

A

Allogeneic

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Q

Donor and recipient are of different species

A

Xenogeneic

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Q

Hyperacute
Acute
Chronic are three types of….?

A

Organ REjection

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Q

Most transplants are…

A

allogeneic

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Q

Type II hypersensitivity is

A

Hyperacute

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Q

Type IV hypersensitivity is…

A

Acute

CD4/8, Direct

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Q

Type III hypersensitivity is…

A

Chronic

Indirect, antibody

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Q

Do you transfuse WBC?

A

NOPE

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Q

What blood accepts all blood?

A

AB+

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Q

What blood gives to all blood?

A

O-

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Q

For a liver transplant you need waht to match

A

Only Blood

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Q

For a kidney transplant you need what to match?

A

HLA and Blodd

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Q

For a Cornea transplant you need what to match?

A

Cornea

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Q

What happens in dendritic cells are in the graft?

A

It kills it (this is type IV sensitivity)

Q

What is GVHD? (Graft-versus-host disease)

A

A transplant T cells attack the host

Q

Prednisolone is the active compound of…?

A

Corticosteroids

Q

IkBa production blocks what fucntion?

A

Function of NFkB

Q

Cyclosporin and Tacrolimus inhibit what?

A

T-Cell Activation

Q

Belatacept and Anti-CD25 prevent what?

A

T-Cell Survival and Proliferation