Organ of Corti Flashcards
Tectorial Membrane
ceiling of the central Scala Media
vibration causes it to move left and right
Basilar Membrane
the floor of the central Scala Media or Cochlear Canal
vibration causes it to move up and down
Hair Cells
the auditory receptor cells
located between the basilar and tectorial membranes
Endolymph
viscous, non-compressible Potassium rich fluid
inside the chamber of the Scala Media
Cilia
are slender protuberances that project from the much larger hair-cell body.
arranged short to long
are bent between the basilar and tectorial membrane
when bent toward the longest cilium…
…K+ gates open
K+ enters t he cell
influx of K+ DECREASE POLARITY from -60mV
chain reaction involving Second Messengers allow Ca++ to enter cell –» release excitatory NT (GLUTAMATE)
the farther the cilia are bent…
…. the greater the impact on the polarity and thus on the release of NT
when cilia bent toward shortest cilium,
…K+ leaves cell (per gradients) and Ca++ is actively pumped out, restoring polarity
typically hair cell potential….
…oscillates (polarized/depolarized/polarized/etc) repeatedly
releasing at least some NT
Hair Cells show ______ hypo-polarization and thus _____ release of NT, depending on ______
graded!
graded!
how far and often Cilia are bent to SPIRAL GANGLIONS
Spiral Ganglions
= ANFs = Auditory Nerve Fibers
fire Action Potentials along axons to Brain