Orbital Diseases Flashcards

1
Q

What is the normal canine and feline orbit like?

A

incomplete - orbital ligament completes it laterally and the floor is left open

  • made up of bone, fat, muscle, nerves, blood vessels, and glands (salivary, lacrimal)
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2
Q

What other structures are close to the orbit in all domestic species?

A
  • mouth
  • nasal cavity
  • ramus of mandible
  • sinuses

all possible origins of disease

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3
Q

Orbit structures:

A
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4
Q

What does orbital position depend on?

A

visual fields

  • horses = monocular, laterally placed orbits
  • dogs, primates = binocular, more medial orbits
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5
Q

What is enophthalmos? What are 5 common causes?

A

sinking in of the globe

  1. ocular pain - retraction
  2. Horner’s syndrome - lack of sympathetic tone
  3. loss of orbital fat
  4. phthisis bulbi, microphthalmia
  5. end-stage extraocular muscle myositis or atrophy following severe cellulitis
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6
Q

What is exophthalmos? What are some causes?

A

protruding globe

  • neoplasia
  • abscess/cellulitis
  • FB
  • masticatory or extraocular muscle myositis
  • salivary mucocele
  • sialoadenitis
  • trauma
  • cysts
  • vascular anomalies
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7
Q

What are the 3 origins of exophthalmos?

A
  1. intraconal - swelling within cone of muscles
  2. extraconal
  3. within the orbit, outside periorbita
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8
Q

How does intraconal exophthalmos present? What are the 2 major etiologies?

A

projection of the globe forward without elevation of the third eyelid

  1. extraocular muscle myositis - always bilateral, must be differentiated from more common abscesses
  2. optic nerve meningiomas
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9
Q

How does extraconal exophthalmos present? What are the 2 most common etiologies?

A

elevation of third eyelid and deviation of the globe (strabismus) depending on mass location —> most common!

  1. retrobulbar abscess/cellulitis
  2. orbital neoplasia
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9
Q

What are the 2 most common etiologies of orbital exophthalmos?

A
  1. masticatory muscle myositis
  2. zygomatic sialoadenitis/mucocele

(no bony wall = orbit issues)

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10
Q

What are 2 examples of nearby structures that can cause exophthalmos?

A
  1. tooth root infections (carnassials!)
  2. neoplasia migrated from nasal cavity, ear, mouth, or sinus (nasal adenocarcinoma)
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11
Q

Why is examining the orbit especially difficult? What needs to be assessed?

A

cannot see it - observe from above!

  • eye/periorbita
  • head and eye position
  • eyelid closure
  • third eye location
  • symmetry
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12
Q

What is the most important aspect of examining the orbit? What else is also commonly done?

A

retropulse the globes

  • perform vision tests, like a menace response, maze, and tracking
  • perform tonometry*, Schirmer tear test, and fluorescein stain
  • open mouth to assess pressure the ramus of the mandible is putting on the globe —> abscesses are much more painful!
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13
Q

What does orbital disease commonly look like? How can it be differentiated?

A

conjunctivitis

  • third eyelid position
  • retropulsion of the globe
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14
Q

How does orbital disease affect vision and intraocular pressure?

A

vision should be normal, there can rarely be some retinal detachment —-> meningioma can affect vision!

usually normal to slightly elevated

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15
Q

What does pain upon closure of the mouth indicate for orbital disease? What is commonly seen?

A
  • abscess
  • cellulitis
  • FB

swollen/red behind last molar (may need anesthesia to observe)

16
Q

What is the classive examination finding indicative of orbital neoplasia?

A

exophthalmos with very little to no pain on opening of the mouth

  • check for epistaxis, air flow from nostril, and pain around the eye
17
Q

How does orbital neoplasia typically progress? What change in the posterior eye may be seen? Pupil?

A

slowly progressive (abscesses would be much more acute)

deviation of the retina due to pressure from mass behind the globe

normal to dilated

18
Q

What are the most common type of tumors of the orbit in small animals?

A

90% are malignant (HSA, lymphoma) and very invasive to surrounding structures

19
Q

What are the most common types of neoplasias seen in the orbits of dogs and cats? What others are also seen?

A
  • DOGS = adenocarcinoma
  • CATS = SCC

lymphoma, osteosarcoma, fibrosarcoma, chondrosarcoma, meningioma, mast cell tumors

20
Q

Exophthalmos characteristics:

A
21
Q

Is radiography commonly used for diagnosing orbital disease? What are MRI and CT usually used for?

A

no —> large amounts of soft tissue surrounding

MRI - optic nerve disease, tumors, soft tissues

CT - soft tissue, tumors, bony involvement

22
Q

What is ocular ultrasound most commonly used for in diagnosing orbital disease? What is its major downfall?

A
  • differentiate abscesses, cellulitis, and tumors
  • guidance for aspirates and biopsies

will not show the borders of tumors

23
Q

Why is it difficult to diagnose orbital neoplasia with ultrasound? What are 3 possible findings?

A

orbital bone interferes

  1. blunting of globe
  2. inability to delineate optic nerve
  3. discrete mass in space
24
Q

What 3 treatments are recommended for orbital abscesses?

A
  1. drainage behind last upper molar or facial swelling with Penrose drain
  2. aerobic/anaerobic bacterial culture
  3. cephalosporins, amoxicillin/clavulanic acid
25
Q

What are the 5 most common bacteria that cause orbital swelling/cellulitis?

A
  1. Staph
  2. E. coli
  3. Bacteroides
  4. Pasturella
  5. Clostridium
26
Q

What medical treatments are recommended for orbital cellulitis?

A
  • not commonly drained
  • systemic broad-spectrum antibiotics for 2-3 weeks
  • pain control with systemic NSAIDs
  • IV fluids, supportive care until able to eat
  • temporary tarsorrhaphy for a week to close eyelids and allow healing
27
Q

What 2 surgical treatments are recommended for orbital neoplasia?

A
  1. exenteration - remove eye and tissues behind it
  2. orbitotomy - take out zygomatic arch and remove neoplasia that has not spread
28
Q

What 3 medical treatments are recommended for orbital neoplasia?

A
  1. chemotherapy - lymphosarcoma
  2. radiation +/- debulking - adenocarcinoma
  3. palliative care depending on extent of tumor infiltration
29
Q

In what species is proptosis most common? What is the most common cause?

A

brachycephalic breeds - better prognosis!

trauma - HBC, bite wounds, dog fights

30
Q

What is proptosis?

A

sudden forward displacement of the globe, which causes eyelid entrapment (unable to see margins), which results in occlusion of venous return

  • must be differentiated from exophthalmos
31
Q

What are 4 favorable prognostic factors associated with proptosis treatment?

A
  1. positive direct or consensual PLR
  2. brachycephalic
  3. short duration with vision intact (positive menace)
  4. normal posterior segment

can be replaced

32
Q

What are 3 unfavorable prognostic factors associated with proptosis treatment?

A
  1. > 3 extraocular muscles avulsed - eye will be looking in the wrong direction and bruised
  2. hyphema
  3. corneal or scleral rupture

usually enucleated

33
Q

Proptosis:

A
  • bruised
  • ulcers from exposure keratitis
  • could be replaced, but unlikely to have vision
34
Q

How is a salvageable proptosis treated? What followup treatments are needed?

A

reposition under general anesthesia ASAP, usually requiring a lateral canthotomy

  • temporary tarsorrhaphy with stents, sutures remain for 1 week
  • systemic antibiotics
  • NSAIDs or steroids
35
Q

What are 6 complications and long-term sequelae associated with proptosis?

A
  1. blindness - only 20% retain vision
  2. dry eye disease
  3. recurrent corneal ulcers
  4. sensory deficits of cornea
  5. lagophthalmos - poor blink
  6. strabismus - rupture of extraocular muscles, most likely medial rectus making them look laterally