Orbit-Sievert Flashcards
Describe the position of the medial & lateral walls of the orbit.
The medial walls are parallel to each other. The lateral walls are orthogonal to each other.
What forms the lens placode or vesicle?
this is formed b/c an out pocketing of the forebrain (diencephalon) induces thickening of the surface ectoderm. This forms the lens placode.
Why is it that the 1st & 2nd Cranial Nerves are not “true” cranial nerves?
this is b/c they both come from an out pocketing of the forebrain. You can’t follow a column all the way up to the forebrain.
Developmentally, where does the lens of the eye come from?
this comes from neural ectoderm
the lens breaks off of the lens placode
Developmentally, where does the cornea come from?
it comes from the remaining surface ectoderm–>once the lens broke off the lens placode.
Developmentally, where does the retina come from?
this comes from an out pocketing of brain tissue.
Where does the optic cup come from?
this comes from an out pocketing of forebrain
So, in total what does an out pocketing of forebrain tissue form?
optic cup retina RPE part of iris part of ciliary bodies
What does RPE stand for? What is its function? What is it sandwiched b/w?
RPE: retinal pigmented epithelium
fcn: keeps light from bouncing around, helps with visual acuity
Sandwiched b/w: choroid below & retinal visual cells above.
Mesenchyme invades the orbit & gives rise to certain structures. What are they?
ciliary body
sclera
choroid
What’s the deal w/ sclera?
so this is equivalent to dura mater.
Actually, the dura mater has 2 layers. The periosteal layer goes along the bones of the orbit. The meningeal layer becomes the sclera after it follows along the optic nerve.
T/F The lens placode and optic cup together give rise to the cornea.
FALSE! The cornea comes from the surface ectoderm & underlying infiltrating mesenchyme.
T/F Cyclopia, anopthalmia & other severe eye defects are often associated with brain defects.
TRUE
What is Coloboma?
Think about the little girl at Sunday school.
This is a common defect where you see a key hole or cat’s eye.
Caused by incomplete closure of the choroid fissure.
Can sometimes have issues with letting too much light in.
What is the choroid fissure?
- *this is a groove that develops for the invaginating hyaloid artery which runs from the posterior chamber to the lens
- *the hyaloid artery later regresses & is only found as the central artery in the optic nerve
- *it leaves the hyaloid canal
- *if this fissure doesn’t close off properly you’ll get coloboma