Oral Sedation Flashcards
What are advantages of oral sedation?
almost universally acceptability, easy, low cost, decreased adverse rxns, no needles or equipment
What are disadvantages of oral sedation?
patient compliance, long latent period, absorption in GI tract, can’t adjust once administered
What is the concept of “rescue” in oral sedation?
BLS/ACLS necessary, support breathing with positive pressure apparatus, possible use of reversal drugs
Approximately __% of people only need a “regular” or “middle” dosage of oral sedative.
70%
What category of drug is most preferred for managing mild to moderate levels of anxiety?
Benzodiazepines
Benzodiazepines produce _______ sedation at therapeutic dosages.
minimal
What are the most popular benzodiazepines?
Diazepam
Midazolam
Triazolam
What is the half-life of Triazolam?
1.5 - 5.5 hours
What is the half-life of Diazepam?
20-70 hours
What are contraindications for using benzodiazepines?
allergy, psychoses, pregnancy, or acute narrow-angle glaucoma, combination with CNS depressants or MAO inhibitors
Children younger than ___________ shouldn’t be given benzodiazepines.
6 months
What two benzodiazepines are commonly used in children?
Midazolam
Diazepam
How long does it take for Triazolam to reach peak plasma levels?
about 1.3 hours
What is the initial dose recommended for Triazolam?
0.25 mg 1 hour prior to treatment
What is the rescue drug for benzodiazepines?
Flumazenil (0.2 mg IV over 15s in adults)
