ORAL PIGMENTATION Flashcards

1
Q

What is Black Hairy Tongue

A
  • Elongation of filiform papillae
  • Due to extrinsic staining
  • e.g. xs smoking, chx, poor OH, wine, broad spectrum antibiotics
  • overgrowth of pigment producing bacteria/fungi
  • areas of white tongue are possible
  • low fibre and dehydration
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2
Q

Black hairy tongue management

A
  • Reassure patient and inform them about BHT
  • OHI
  • Diet high in fibre and hydration
  • Smoking VBA/drinking
  • Avoid XS tongue brushing as this can exacerbate it
  • Oxidising mouthwash (Peroxyl)
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3
Q

What is Amalgam tattoo

A
  • common in mandibular gingiva and alveolar mucosa
  • May be due to XLA of tooth or removal of restoration made of amalgam
  • Oral pigmentation of slate grey/blue black macule
  • No elevation
  • No change in size but margins will blur
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4
Q

What is a Graphite tattoo

A
  • Common in the palate of children
  • second most common cause of exogenous localised oral pigmentation
  • Biopsy to eliminate malignancy
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5
Q

Mangement of amalgam/graphite tattoo

A
  • Radiograph would show amalgam in tissue, depending on the density of surrounding bone and KV exposure/voltage
  • Biopsy to eliminate malignancy
  • Reassure patient
  • Can be removed with Q-switch ruby laser (shatters tattoo and particles removed by lymphatics)
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6
Q

Metal salt deposition

A
  • Metal sulphides along the gingival margin
  • Bismuth, lead, mercury
  • present in crevicular fluid and precipitate as sulphides by hydrogen sulfide by plaque microorganisms
  • Linear grey/black lines along gingiva as lead/burtons lines
  • can be confused as subgingival calculus
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7
Q

Ethnobotanical tattoo

A
  • common in africa
  • females as a rite of passage
  • Thought to improve OH and eliminate bad breath
  • tattoo of gingiva with soot covered thorns
  • thought to be used as a remedy for dental pain
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8
Q

Oral melanotic macule

A
  • Benign localised area of increased melanin
  • effects any mucosal surface but skin is more common
  • common in F
  • Lesion on lip due to sun damage
  • Homogenous flat brown/black regular border
  • <5mm
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9
Q

Management of a oral malenotic macule

A
  • Biopsy to eliminate malignancy and avoid long term follow up
  • Lip lesions could be monitored if not suspicious
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10
Q

Oral melanoma

A
  • rare
  • palate is most common but can effect anywhere (lip/gingiva)
  • brown/black but 30% as amelanotic
  • irregular border and colour (non-homogeneous)
  • can be nodular (alarm bells for malignancy)
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11
Q

Differential diagnosis for oral melanoma

A
  • oral melanotic macule
  • amalgam tattoo
  • graphite tattoo - palate is common here
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12
Q

Oral melanoma prognosis + metastasis

A
  • oral melanoma has a poor prognosis 5-20% 5year survival

- metastasis to lymph, lungs, liver (3Ls)

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13
Q

Ecchymosis aetiology

A
  • blue/black/purple bruising due to:
    1) trauma e.g. fracture mandible
    2) underlying palatal/coagulation disorder
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14
Q

Varcies

A
  • Lower lip/sublingual
  • vein dilation
  • blue & lobulated
  • blanch on pressure
  • may have hard areas due to thrombosis/ clacified phleboliths forming
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15
Q

Localised oral pigmentation

A
black hair tongue
amalgam/graphite tattoo
metalic salts
alcohol eg. red wine
tobacco/betel use
melanotic macules
malignant melanoma
kaposi sarcoma
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16
Q

Generalised oral pigmentation causes

A

DEVELOPMENTAL

  • racial pigmentation
  • peutz-jeghers
  • pigmented naevi

MEDICATION e.g. tetracylines/chloroquine

HABITS

  • smoking
  • betel use

POST-INFLAMMATORY

ASSOCIATED W SYSTEMIC DISEASE

  • endocrine eg. addisons disease (blue/black), cushings disease
  • metabolic
  • infective
17
Q

What is Peutz Jeghers syndrome

A
  • autosomal dominant condition
  • Mutation in LKB1 or ch19 which codes for serine-threonine-kinase (plays a role in apoptosis)
  • multiple perioral/vermillion border freckles/melanotic macules
  • pigmented spots intraorally, extremities, nasal and rectal mucosa
  • melanotic macules are not malignant
  • Haematomatous intestinal polyps + abnominal and rectal bleeding
  • risk of internal malignancy
  • monitor this!
18
Q

What does betel nut cause

A
  • TSL as its abrasive
  • oral submucous fibrosis
  • lichenoid reaction (mucositis)
  • epithelial dysplasia
  • increase risk of malignancies/OSCC
  • leukoplakia
  • staining (buccal+teeth)
19
Q

Manage betel/paan use

A
  • VBA betel nut cessation
  • Nicotine replacement patches
  • biosy to eliminate malignancy
20
Q

Drug-induced hyperpigmentation (BLUE/GREY VS BROWN)

A

BLUE GREY:

  • fluoxetine
  • chloroquine
  • minocycline/tetracycline
  • amiodarone

BROWN

  • minocycline/doxycycline/tetracycline
  • propanolol
  • busulphan

OTHERS
arsenic+sulphydryl groups =melanin deposit
phenothiazine+minocycline react w melanin

21
Q

ADDISONS DISEASE

A
  • insufficiency / atrophy of adrenal cortex
  • increased ACTH= increased MSH= increase melanin
  • BLUE BLACK ORAL PIGMENTATION
  • pigmentation/bronzing on cutaneous sun exposed areas
  • genital pigmentation
  • side effect of systemic corticosteroids
22
Q

Addison disease management

A

life long steroid hormone replacement therapy (HRT)

23
Q

Cushings disease

A
  • xs cortisol hormone
  • oral pigmentation blue/black
  • side effect of systemic corticosteroids