Oral Mucosa part II Flashcards
Name some host derived enzymes found in the GCF.
Acid phosphates Alkaline phosphatase Alpha 1 antitrypsin Arulsulphatse Aspartate aminotransfarase B-glucuronidase Cathespin D, G Matrix metalloprotiens MMPS Elastase Plaminogen activators
Where does elastase come from? What does high levels of elastase indicate?
PMNs. Disease
If there are high levels of anitbodies in the GCF what does that indicate?
That the sulcus has turned into a pocket.
Name some bacterial derived enzymes in the GCF.
Acid phosphates Alkaline phosphatase Collagenase Hyaluronidase phosphlipase A phospholipase c Bacterial proteinases ENDO and EXOpeptidases
Name the cellular elements of the GCF (3)
Bacteria desquamated epithelial cells leukocytes PMNs, lymphocytes, monocytes
Where do leukocytes migrate through into the sulcus in healthy tissue?
Sulcular epithelium
List the electrolytes found in the GCF (5)
Potassium K Sodium Na Calcium Ca Magnesium Mg Fluoride F
During inflammation, _____ and ____ concentrations have a positive correlation with _____ ratio in the GCF.
Ca and Na Na/K
List (2) organic compounds found in the GCF.
GLUCOSE hexosamine Hexuronic acid
Glucose concentration in the gingival fluid is _____ times greater than that in _____.
3-4 serum
The excess glucose in diabetic patients can be used by what and cause what?
Bacteria lactic acid that leads to caries
List the metabolic end products of bacteria (6)
Lactic Acid Endotoxins Urea Hydroxyproline Cytotoxic substances Hydrogen sulfide - smelly!!
What are cytokines?
Potent local mediators of inflammation. Produced by a variety of cells Communication between white blood cells
What can cytokine be diagnostic markers for in the oral mucosa?
Periodontal disease
List (5) types of cytokines.
Interleukin 1alpha Interleukin 1beta interleukin 6 interleukin 8 tumor necrosis factor
What interleukins have pro-inflamatory affects?
IL 1 alpha IL 1 beta * can stimulate bone reposition or formation
What is prostaglandin E2?
inflammatory mediator A product of the cyclooxyrgenase path
Where the levels of PGE2 elevated or depressed in patients with periodontitis?
ELEVATED!
What color is the attached gingiva?
Light pink, coral pink * may be pigmented depending on skin color. Darker skin - darker attached gingiva
What are the functions of the attached gingiva?
Withstand mechanical forces Prevents free gingival from being pulled away from the tooth when tension is applied to mucosa (lip being pulled out)
What are stipplings?
The attachement points of fibers to the gingival tissue, cement, and bone. Rete pegs and epithelial projections.
Healthy texture is ______
stippled
Does the absence of stippling mean anything?
NO! Presence of stippling does not mean disease.
Maxillary ATTACHED GINGIVA width: * incisors:_______ * premolar:__________
3.5 - 4.4 mm 1.9 mm * more recession can occur in the incisors before it is huge concern.
Mandibular ATTACHED GINGIVA width: * Incisors: _______ * Premolars: ________
3.3 - 3.9 mm 1.8 mm
The entire palate is attached tissue? T or F
True
Should lacerations of the palatal rugae be noted in the patients chart? Why?
Yes! It is a clinical finding. Can occur due to sharp foods.
Interdental paplla
should extend up between the teeth until tooth contact. Fill the entire inter proximal space.