LESIONS Flashcards
When does an INITIAL lesion begin?
2-4 days
What happens histologically for an INITIAL lesion?
Vasodilation subjacent to junctional epithelium
Exudation of fluid from the gingival sulcus
Increased migration of leukocytes into the JE and GS
Presence of serum proteins (fibrin, extra vascularly)
Alteration of the most coronal portion of the JE
Loss of perivascular collagen
What happens clinically for an INITIAL lesion?
Appears clinically healthy
No periodontal pocket
No radiographic evidecne of bone loss
When does EARLY lesion occur?
4-7 days
What happens histologically for a EARLY lesion?
Accentuation of features of the initial lesion
Accumulation of lymphoid cells adjacent to JE
Cytopathic alterations of fibroblasts
Further loss of collagen fiber network of the marginal gingiva
Beginning proliferation of basal cells of JE
What happens clinically for an EARLY lesion?
Gingivitis
Changes in gingival color, contour, consistencey
No periodontal pocket
No radiographic bone loss
When does an ESTABLISHED lesion occur?
2-3 weeks
What happens histologically for an ESTABLISHED lesion?
Persistence of the manifestation of acute inflammation
Predominance of plasma cells without bone loss
Presence of IG extravscularly in the CT and JE
Continuing loss of CT noted in the early lesion
Proliferation, apical migration, and lateral extension of JE
Early pocket formation may or may not be present
What happens clinically for and ESTABLISHED lesion?
Gingivitis (chronic form)
Changes in gingival color, contour, consistencey and BOP
No periodontal pocket
No radiographic bone loss
When does and advanced lesion occur?
> 3 weeks
What happens histologically for an ADVANCED lesion?
Persistence of features in established lesion
Extension into alveolar bone and PDL with significant bone loss
Continued loss of collagen subjacent to pocket epithelium
Cytopathically altered plasma cells
Formation of periodontal pockets
Periods of quiescence and exacerbation
Conversion of distant bone marrow into fibrous CT
weidspread manifestations of inflammatory/immunopathologic reactions
What happens clinically for an ADVANCED lesion?
Periodontitis Changes in gingival color, contour Bleeding on probing Periodontal pocket formation Alveolar bone loss as shown on radiographs
What complex are the periodontal causing bacteria found?
Red and orang
Are periodontal causing bacteria early or late colonizers?
Late
What are he periodontal causing bacteria? (7)
Aggregatibacter actinomycetemcomitans Porphyromonas gingivalis Prevotella intermedia Tannerlla forsythia Fusobacterium nucleatum Pretpstretococcus micros Campylobacter rictus
