Oral Microbiome/Systemic Disease Flashcards
What are the newer therapies that are designed to encourage healthy communities?
- Probiotics
- Prebiotics
- Targeted antimicrobials
Describe the translocation of bacteria in causing systemic infection?
Distant site infection seeded by oral bacteria
In the translocation of toxins, does the bacteria from the mouth gain access to the circulatory system?
Not necessarily. Toxin from the bacteria gains access and moves to different site.
T/F: Host hyper-inflammatory phenotype (IL-1 polymorphism) can predispose patients to oral-systemic disease connections.
True
T/F: Steptococci (oral bacteria) constitutes 60% of the bacterial community involved in infective endocarditis.
True
Does antibiotic prophylaxis during dental procedures prevent bacteremia?
In theory it should, but in practice it does not.
T/F: There is solid evidence that dental procedures are associated with infective endocarditis.
False
What is the most important factor for preventing bacteremia in the mouth?
Optimize oral hygiene to keep bacterial load low
T/F: The evidence that oral hygiene can help prevent lung infection is poor.
FALSE
High quality evidence
T/F: Periodontitis is associated with preterm birth, low birthweight, and pre-eclampsia.
True
T/F: Strong evidence of causation between oral bacteria and preterm birth.
FALSE
T/F: Treatment of periodontitis improves glycemic control.
True
T/F: The evidence connecting periodontitis and diabetes is very strong.
FALSE
Weak to moderate
T/F: A causative relationship has been established between periodontitis and cardiovascular disease.
FALSE
Only a link has been established
What type of cancer has been linked to periodontitis?
Pancreatic cancer
