Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

AU17: Oral Microbiology > Caries > Flashcards

Caries Flashcards

You may prefer our related Brainscape-certified flashcards:
Biology 101 flashcards
1
Q

Bacteria in biofilms on the surface of the tooth produce ___________ from glycolysis of sugars.

A

Lactic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Lactic acid drops ___ and the mineral matrix of the tooth dissolves.

A

pH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Why is the initial demineralization only on the subsurface, leaving a thin layer of enamel overlying the lesion?

A

Pellicle proteins stabilize the surface

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Once ___________ occurs, biological repair is no longer possible.

A

Cavitation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Why is remineralized tooth structure stronger than virgin enamel?

A

Incorporation of fluoride

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the most important property of caries-causing bacteria?

A

They continue to produce acid at low pH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What species cause initial caries?

A
  1. Strep mutans
  2. Other strep (sobrinus, salivarius)
  3. Veillonella
  4. Actinomyces
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What species cause caries progression?

A
  1. S. Mutans
  2. Lactobacillus casei, rhamnosus, gasseri, fermentum
  3. Bifidobacterium and scardovia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the most common supragingival organism?

A

Streptococci

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the only nutrient source for S. Mutans?

A

Carbohydrates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

T/F: S. Mutans is good at surviving during feast and famine.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What strep is very closely related to strep mutans?

A

S. Sobrinus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

T/F: S. Mitis is a caries causing bacteria.

A

False

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the earliest acquired oral bacteria?

A

S. Mitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What strep is found in healthy plaque and is a good initial colonizer of the pellicle?

A

S. Sanguinis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

T/F: S. sanguinis produces cannot produce lactic acid at low pH.

A

True

17
Q

What bacteria may be associated with root caries?

A

Actinomyces

18
Q

T/F: Actinomyces is anaerobic.

A

True

19
Q

T/F: Veillonella ferments carbohydrates to create lactic acid.

A

FALSE

Protects against acid by fermenting lactate

20
Q

At what point do lactobacilli play a role?

A

Established or deep lesions

21
Q

What is the initial process of attachment for caries development?

A

S. Sanguinis binds to pellicle -> s. Mutans binds to s. Sanguinis -> s. mutans makes extracellular matrix

22
Q

How does S. Mutans make extracellular matrix?

A

Uses glucosyltransferase (Gtf) to make ECM from sucrose

23
Q

What is the major component of the ECM?

A

Glucan

24
Q

T/F: S. Sanguinis does better than s. Mutans at low pH.

A

False

S. Mutans dominates at low pH

25
Q

What is the major difference between good and bad bacteria?

A

Good = grow and make acid at high pH but stop at low pH

Bad = Grow and make acid best at low pH

26
Q

What is the short term effect of sugar consumption?

A

Drops the oral pH

27
Q

What is the long term effect of sugar consumption?

A

Selection for cariogenic bacteria over healthy bacteria

28
Q

What would be the targets of a caries vaccine?

A

Gtf and glucan binding proteins

29
Q

What are the two types of vaccines under investigation for caries?

A

Active immunity = mucosal vaccination; need adjuvants

Passive immunity = antibodies grown in tobacco plants and cows milk

30
Q

What is replacement therapy?

A

Replace wild-type S. Mutans with strain that does not produce lactate

31
Q

What is a STAMP?

A

Antibody guided antimicrobial

AU17: Oral Microbiology (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions