Oral Manifestations of GI Disease Flashcards
Where do the ulcers of recurrent apthous stomatitis not usually occur? (in otherwise healthy patients)
Keratinized mucosa (hard palate, gingiva, dorsum of the tongue)
What GI disease can recurrent apthous stomatitis be a direct manifestation of?
Crohn’s disease
What do the ulcers of recurrent apthous stomatitis look like on histology?
It’s non-specific:
Mixed lymphocytic infiltration, with plasma cells and PMNs.
PMNs going deep into tissue is more suggestive of recurrent apthous stomatitis.
有争议的
contentious
What’s an oral lesion that pathognomonic for Crohn’s disease?
Ulcers in the mucobuccal folds
What will a biopsy from oral CD show?
Granulomas are often present.
not pathognomonic - granulomas can be caused by foreign bodies, TB, sarcoid, etc.
What’s the deal with oral lesions in UC patients?
They’re associated with, but not UC itself.
Tend to be apthous ulcers… but there’s no pathognomonic oral lesion.
Angular cheilitis happens too…
What are 2 oral manifestations of celiac?
Ulcerations
Enamel pitting - if the celiac occurs before the teeth have finished developing.
DDx for enamel erosion in an adult?
GERD
Bulimia
With what GI disease are supernumerary teeth strongly associated?
FAP aka. Gardner’s Syndrome
not pathognomonic, though
For what disease are multiple jaw osteomas and/or multple odontomas pathognomonic?
FAP aka. Gardner’s Syndrome
What are Fordyce granules?
With what are they associated (if present at a young age)?
Ectopic sebaceous glands in the mouth.
If present in a child, they’re strongly suggestive of HNPCC aka. Lynch Syndrome.
(they themselves don’t cause problems)
What’s the oral manifestation of Peutz-Jeghers syndrome?
Diffuse “freckling” of lips, peri-oral skin, etc.
can also get this on the fingertips
What is pyostomatitis vegetans? With what is it associated?
Lots of “snail-track” pustules, ulcerations on the lips / oral cavity.
Can be manifestation of IBD or GI malignancy.
(surprisingly not as uncomfortable as it looks)
What does pyostomatitis vegetans look like on histology?
Thickened epithelium
Suprabasilar clefting
Eosinophilic abscesses (mixed with other leukocytes)
