Oral Histo Study guide (the first one) Flashcards
Paracrine
Cell to cell communication/regulation
Autocrine
Cell to self-communication-communication
At what stage is the blastocyst between 3-4 days?
Morula
How long does the blastocyst take to develop into a blastula?
4-5 days
How long does the blastocyst take to develop into a gastrula?
8-16 weeks
During what time period is the blastocyst most susceptible to teratogens?
8-16 weeks of development
What layer does the notochord arise from?
Mesoderm
What layer does the neural tube come from?
Ectoderm
What layer gives rise to the enamel and CNS?
Ectoderm
Where does the first brachial arch occur?
Where the mandible is going to grow
To what area does the 6th arch contribute to cartilage?
The throat
Where is Reichert’s cartilage found?
In the 2nd pharyngeal arch
What does Reichert’s cartilage form?
The stapes
A brachial groove is an ____ arch separation point
external
A brachial pouch is an ____ arch separation point
internal
What part of the skull forms the face?
Viscerocranium
What is the only membranous bone below the neck?
Clavicle
Alveolar bone is similar to what type of bone, due to having a high protein and low mineral content?
Woven bone
Occipital bone is the only ___ bone in the head
endochondral
Epiphyseal plate is where growth occurs and is made of what type of cartilage?
Hyaline
Hyaline cartilage is laid on what type of collagen?
1
What are the pits on the surface of the bone that an osteoclast sits in?
Howship’s lacunae
What type of epithelium constitutes oral epithelium?
Stratified squamous epithelium, can be both keratinized and non-keratinized
The dental lamina is a lyer over the ectomesenchyme that goes on to form what two structures?
Maxilla and mandible
Ameloblast forms what?
Enamel
The dental papilla forms what, and contains what type of cell?
Forms dentin, contains odontoblasts
Dental follicle is a sac that holds what two structures?
The developing enamel organ and dental papilla
What does the enamel organ contain? What does it sit over?
It contains the outer and inner enamel epithelium and sits over the dental papilla
What does the Hertwig epithelial root sheath initiate?
Formation of the dentin in a tooth’s root
The primary epithelial band gives rise to what two structures?
- Dental lamina (first evidence of tooth development at 6th week in utero)
- Vestibular lamina (space bordered by the junction of the gingiva and the tissue of the inner cheek)
In what stage of amelogenesis do cells become ameloblasts and repolarize by reciprocal induction?
Secretory
What responsibility does Tome’s processes have in regards to amelogenesis?
They lay down inter-rod enamel that is made of hydroxyapatite
What is the protein in enamel that constitutes 90% of the enamel matrix?
Amelogenin
When are intrinsic fibers present in the mouth?
When repair is done.
What are the four types of calcified tissue in the human body?
Bone, cementum, dentin and enamel
What is the collagen that is the primary component of bone, cementum and dentin, and comprises the PDL
Type 1 collagen
What is the range of the anticaries impact of fluoride?
0.7 to 1 ppm (1 ppm= 1 mg/kg)
What is the range of mild fluorosis? What is another term for this?
2-5 ppm, “mottled enamel”
What is the amount of fluoride one must ingest to suffer severe fluorosis? What does this cause?
5 and above ppm, causing hypoplastic pits
What happens to someone who ingests 100 and above ppm of fluoride?
Respiratory failure
What is hypoplasia?
Incomplete development of a tissue or organ (i.e. enamel)
What is the most common manifestation of orofacial clefts?
Lip and palate, at 45%
What are three important clinical manifestations of Pierre Robin syndrome?
- Micrognathia
- Cleft palate
- Glossoptosis
Where are commissural lip pits located? Are they common or not?
At the corners of the mouth on the vermillion border, common
Where are paramedial lip pits? Common or not?
Lower lip, rare
What are three results of Ascher syndrome?
- Double lip
- Blepharochalasis (folds of tissues on upper eyelids)
- Thyroid enlargement
What are Fordyce granules? Are they common?
Sebaceous glads on the oral mucosa, very common at 80% of people