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Histo > Ivan Slides > Flashcards

Ivan Slides Flashcards

1
Q

Bifid uvula: minimal manifestation of what?

A

Cleft palate

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2
Q

Pierre Robin sequence: What are the three characteristics?

A
  1. Mandibular micrognathia
  2. Glossptosis with airway obstruction
  3. Cleft palate
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3
Q

With Pierre Robin sequence, there is constraint of mandibular growth in utero. This results in failure of the tongue to descend, causing what two issue?

A
  1. Fusion of palatal shelves

2. Adequate respiration

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4
Q

What is the mortality rate for Pierre Robin?

A

2-12% (usually due to respiratory issues)

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5
Q

Paramedian lip pits usually invaginate which lip?

A

Lower

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6
Q

What gene is impacted causing Paramedian lip pits?

A

IRF6

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7
Q

What syndrome are paramedian lip pits the most common manifestation of?

A

van der Woude syndrome

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8
Q

What is the prevalence of Commisural lip pits in adults and children?

A

Adults: 10-20%
Children: <1%

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9
Q

Where are commissural lip pits?

A

At the corners of the mouth on vermillion border in depth?

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10
Q

What syndrome is double lip occasionally associated with?

A

Ascher syndrome

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11
Q

How prevalent is fissured tongue?

A

2-5%

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12
Q

How many children die from complications due to Beckwith-Wiedemann syndrome?

A

10-20%

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13
Q

What is (generally) Beckwith-Wiedemann syndrome?

A

A pediatric overgrowth disorder associated with predisposition to cancer

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14
Q

How rare is an ectopic thyroid at base of tongue?

A

1 in 100K people (with a female predilection)

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15
Q

What is the most common symptom of an ectopic thyroid at the base of tongue?

A

Dysphagia

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16
Q

In greater than what percent of patients is the lingual thyroid the only thyroid tissue for an ectopic thyroid at the base of the tongue?

A

75%

17
Q

For a thyroglossal duct cyst, how common is it in infancy/childhood?

A

2.2: 100,000

18
Q

In what percent of patients of thyroglossal duct cyst is the cyst located in the infrahyoid position and it moves up and down with swallowing?

A

75%

19
Q

What is the most common non-odontogenic cyst of the gnathic bones?

A

Nasopalatine duct cyst (incisive canal cyst)

20
Q

What causes the median palatal cyst to develop?

A

It comes from entrapped epithelium during the embryologic fusion of palatal processes

21
Q

What is the most common branchial cleft anomaly?

A

The branchial cleft cyst

22
Q

What is the second most common branchial cleft cyst at 90%?

A

Second branchial cleft cyst?

23
Q

How much more common is coronoid hyperplasia in men compared to women?

A

5:1

24
Q

How much more common in women than men is condylar hyperplasia?

A

3 times

25
Q

Where are 85% of Stafne defects found?

A

In the posterior body of the mandible beneath the inferior alveolar canal

26
Q

Where are 10 to 15% of Stafne defects found?

A

The anterior mandible (and associated with sublingual gland)

27
Q

How much more common is the Stafne defect in men compared to women?

A

6:1

28
Q

Where are lateral soft palata fistulas most common?

A

Anterior tonsillar pillars, bilaterally

29
Q

What percent are children at risk for cancer in connection with isolated lateralized overgrowth (hemihyperplasia)?

A

5%

30
Q

During what decades is the onset of Parry-Romberg syndrome?

A

First to second

31
Q

How long does the bone in Parry-Romberg syndrome atrophy before it stabilizes?

A

5-20 years

32
Q

How common is Crouzon syndrome?

A

1 in 65K

33
Q

What gene is mutated to cause Crouzon syndrome?

A

FGFR2

34
Q

What branch/es is/are responsible for Treacher Collins syndrome (mandibulofacial dysostosis)?

A

1st and 2nd

35
Q

What gene is implicated in Treacher Collins syndrome (mandibulofacial dysostosis)?

A

TCOF1

36
Q

Some cleft palates may present as what type of clefts only?

A

Submucosal

Histo (7 decks)

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