Ivan Slides Flashcards
Bifid uvula: minimal manifestation of what?
Cleft palate
Pierre Robin sequence: What are the three characteristics?
- Mandibular micrognathia
- Glossptosis with airway obstruction
- Cleft palate
With Pierre Robin sequence, there is constraint of mandibular growth in utero. This results in failure of the tongue to descend, causing what two issue?
- Fusion of palatal shelves
2. Adequate respiration
What is the mortality rate for Pierre Robin?
2-12% (usually due to respiratory issues)
Paramedian lip pits usually invaginate which lip?
Lower
What gene is impacted causing Paramedian lip pits?
IRF6
What syndrome are paramedian lip pits the most common manifestation of?
van der Woude syndrome
What is the prevalence of Commisural lip pits in adults and children?
Adults: 10-20%
Children: <1%
Where are commissural lip pits?
At the corners of the mouth on vermillion border in depth?
What syndrome is double lip occasionally associated with?
Ascher syndrome
How prevalent is fissured tongue?
2-5%
How many children die from complications due to Beckwith-Wiedemann syndrome?
10-20%
What is (generally) Beckwith-Wiedemann syndrome?
A pediatric overgrowth disorder associated with predisposition to cancer
How rare is an ectopic thyroid at base of tongue?
1 in 100K people (with a female predilection)
What is the most common symptom of an ectopic thyroid at the base of tongue?
Dysphagia
In greater than what percent of patients is the lingual thyroid the only thyroid tissue for an ectopic thyroid at the base of the tongue?
75%
For a thyroglossal duct cyst, how common is it in infancy/childhood?
2.2: 100,000
In what percent of patients of thyroglossal duct cyst is the cyst located in the infrahyoid position and it moves up and down with swallowing?
75%
What is the most common non-odontogenic cyst of the gnathic bones?
Nasopalatine duct cyst (incisive canal cyst)
What causes the median palatal cyst to develop?
It comes from entrapped epithelium during the embryologic fusion of palatal processes
What is the most common branchial cleft anomaly?
The branchial cleft cyst
What is the second most common branchial cleft cyst at 90%?
Second branchial cleft cyst?
How much more common is coronoid hyperplasia in men compared to women?
5:1
How much more common in women than men is condylar hyperplasia?
3 times
Where are 85% of Stafne defects found?
In the posterior body of the mandible beneath the inferior alveolar canal
Where are 10 to 15% of Stafne defects found?
The anterior mandible (and associated with sublingual gland)
How much more common is the Stafne defect in men compared to women?
6:1
Where are lateral soft palata fistulas most common?
Anterior tonsillar pillars, bilaterally
What percent are children at risk for cancer in connection with isolated lateralized overgrowth (hemihyperplasia)?
5%
During what decades is the onset of Parry-Romberg syndrome?
First to second
How long does the bone in Parry-Romberg syndrome atrophy before it stabilizes?
5-20 years
How common is Crouzon syndrome?
1 in 65K
What gene is mutated to cause Crouzon syndrome?
FGFR2
What branch/es is/are responsible for Treacher Collins syndrome (mandibulofacial dysostosis)?
1st and 2nd
What gene is implicated in Treacher Collins syndrome (mandibulofacial dysostosis)?
TCOF1
Some cleft palates may present as what type of clefts only?
Submucosal
