Oral environment and dry mouth Flashcards
What bacteria influence cariogenic disease?
viridans streptococci.
What are some gram negative anaerobic bacteria
porphyromonas, prevotella, fusobacterium
what bacterium has a protective effect against caries
veillonella parvula is protective as it takes acid and converts it to weaker acid
what are mucins?
salivary glycoproteins.
form 90%of acquired pellicle, 26% of salivary proteins AKA A LOT OF THEM.
what are the types of mucin?
- abundant
- lower surface tension
- 2 types:
- OLIGOMERIC - MUC 1 TYPE: GEL FORMING, NON ANCHORED, ABUNDANT IN SALIVA, FLUSHES AWAY BACTERIA .- MONOMERIC - MUC 2 TYPE: NON GEL FORMING, ANCHORED, ABUNDANT ON SURFACES. ALLOWS FOR ATTACHMENT OF BACTERIA. ANTIBACTERIAL AND ANTIFUNGAL?.
What is the function of prolein rich proteins in the oral microbiome?
they are PROMOTERS OF BACTERIAL ADHESION.
what are the 3 types of prolein rich proteins?
- acidic –> pellicle, control Ca and phosphate, antibacterial
- basic –> protective
- glycosylated –> newly formed pellicle
what is the function of statherins
BLOCK NUCLEATION SITES - reduce the amount of calcium and phosphate deposition.
what is the main glycoprotein of the pellicle?
mucin
What are glucosyltransferases? What do they produce?
What is their product importnat?
Bacterial products. Produce glucans, which can act as ADHESION SITE for bacteria and carbohydrate storage/ sticky polysaccharides (AKA NUTRITION FOR BACTERIA)
What are glucans? What are the two types?
glucans are glucose polysaccharides.
2 types:
- dextrans (water soluble)
- mutans (water insoluble)
what is the function of cystatins?
inhibit cysteine proteases, ANTIBACTERIAL AND ANTIVIRAL.
function of histatins?
ANTIBACTERIAL AND ANTIFUNGAL
What is the function of lysozymes
break down the walls of bacteria by interfering with CROSSLINKS
what is the function of lactoferrin
BINDS AND SEQUESTERS IRON HENCE INTERFERES WITH ACCESS TO IRON FOR BACTERIA.
(ANTIBACTERIAL, ANTIFUNGAL, ANTIVIRAL.)
