Option D4 The Heart Flashcards
Cardiac muscle cells
Heart cells that…
- Are myogenic (contract without stimulation by the central nervous system)
- Are branched, allowing for faster signal propagation and contraction in three dimensions
- Are not fused together, but connected by intercalated disks
- Have more mitochondria because they are more reliant on aerobic respiration than skeletal muscle
Structural features of cardiac tissue
- Muscles have a longer period of contraction and refraction, which is needed to maintain a viable heart beat
- Tissue does not become fatigued (unlike skeletal muscle), allowing for continuous, lifelong contractions
- Interconnected network of cells is separated between atria and ventricles, allowing them to contract separately
Result of intercalated discs
While electrical signals can pass between cells, each cell is capable of independent contraction.
- Coordinated contraction of cardiac muscle cells is controlled by specialized auto-rhythmic “pace-making” cells
Sinoatrial (SA) node
A cluster of cardiomyocytes within the wall of the right atrium that direct the contraction of the heart tissue.
- Primary pacemaker that controls heart rate
- Sends out electric signals that stimulate heart contractions
Atrioventricular (AV) node
A separate node that separates atrial and ventricular contractions.
Atrial contraction (systole)
- SA node signals for the heart to contract
- Electric signal is transmitted via gap junctions to the atrial myocardium
- Atria contract, forcing blood into the ventricles
- SA node sends signals to the AV node simultaneously
Time lag between atrial and ventricular systole
Optimizes blood flow between chambers, allowing blood to fill ventricles before AV valves close.
Bundle of His
A specialized bundle of cardiomyocytes that innervate the Purkinje fibers, causing cardiac muscle to contract.
Ventricular contraction (systole)
- AV node is triggered by signals of the SA node
- Signals are sent down the septum via the Bundle of His
- Bundle of His triggers Purkinje fibers in the wall of ventricles
- Ventricles contract, forcing blood into the arteries
Diastole
A relatively long recovery period that allows the heart to passively refill with blood between beats.
- Recovery period helps prevent heart tissue from becoming fatigued
Structural features and its contribution to functional properties
- Cardiac muscle has a longer period of contraction and refraction, which is needed to maintain a viable heart beat
- The heart tissue does not become fatigued (unlike skeletal muscle), allowing for continuous, life long contractions
- The interconnected network of cells is separated between atria and ventricles, allowing them to contract separately
Specialized cluster of cardiomyocytes
- This cluster of cells is collectively called the sinoatrial node (SA node or SAN)
- The sinoatrial node acts as a primary pacemaker, controlling the rate at which the heart beats (i.e. pace ‘making’)
- It sends out electrical signals which are propagated throughout the entire atria via gap junctions in the intercalated discs
- In response, the cardiac muscle within the atrial walls contract simultaneously (atrial systole)
Fibrous cardiac skeleton composed of connective tissue
- This connective tissue functions to anchor the heart valves in place and cannot conduct electrical signals
- The signals from the sinoatrial node must instead be relayed through a second node located within this cardiac skeleton
- This second node is called the atrioventricular node (or AV node) and separates atrial and ventricular contractions
- The AV node propagates electrical signals more slowly than the SA node, creating a delay in the passing on of the signal
Two sets of valves located in the heart:
- Atrioventricular valves (tricuspid and bicuspid) prevent blood in the ventricles from flowing back into the atria
- Semilunar valves (pulmonary and aortic) prevent blood in the arteries from flowing back into the ventricles
Heart sounds
- The first heart sound is caused by the closure of the atrioventricular valves at the start of ventricular systole
- The second heart sound is caused by the closure of the semilunar valves at the start of ventricular diastole