Opthalmology Flashcards
Rheumatoid arthritis: ocular manifestations
Ocular manifestations of rheumatoid arthritis are common, with 25% of patients having eye problems
Ocular manifestations
keratoconjunctivitis sicca (most common)
episcleritis (erythema)
scleritis (erythema and pain)
corneal ulceration
keratitis
Iatrogenic
steroid-induced cataracts
chloroquine retinopathy
Beta blockers such as timolol work in primary open-angle glaucoma by reducing aqueous production
the affected and normal eye appears to dilate when light is shone on the affected
RAPD
Angioid retinal streaks
are seen on fundoscopy as irregular dark red streaks radiating from the optic nerve head. They are caused by degeneration, calcification and breaks in Bruch’s membrane .
Causes
pseudoxanthoma elasticum
Ehler-Danlos syndrome
Paget’s disease
sickle-cell anaemia
acromegaly
Holmes-Adie syndrome
association of Holmes-Adie pupil with absent ankle/knee reflexes
examples of anti-VEGF agents include
ranibizumab, bevacizumab and pegaptanib,. The agents are usually administered by 4 weekly injection.
This condition, also known as *****, is characterised by a dilated pupil that reacts slowly to light but has a normal or near-normal response to accommodation. It often presents unilaterally and may be accompanied by absent tendon reflexes.
Adie’s tonic pupil,
The**** is a small, irregular pupil that constricts normally with accommodation but does not react to light. It is typically bilateral and associated with neurosyphilis, specifically tertiary syphilis.
Argyll-Robertson pupil