Opportunistic Practice Flashcards
• Originally classified as a protozoan
• DNA in close relationship to ascomycetes
• Inhabit the lungs of animals (rats, mice, dogs, cats, ferrets, rabbits)
- most common in rats
Pneumocystis jirovecii
• P. carinii
• are extracellular pathogens, grow only to the the surfactant layer above the alveolar epithelium
Pj
• Pneumonia in immunocompromised patients; dissemination rare
Pj
• Human disease confined to interstitial plasma cell pneumonitis in malnourished infants & immunosuppressed patients
Pj
MUCORMYCOSIS
Zygomycosis
• Most prevalent:
Rhizopus oryzae
MUCORMYCOSIS
Zygomycosis
• Leading pathogens:
Rhizopus,
Rhizomucor,
Lichtheimia,
Cunninghamella,
Mucor, etc.
• An opportunistic mycosis caused by a number of molds classified in the order Mucorales.
MUCORMYCOSIS
Zygomycosis
MUCORMYCOSIS
Zygomycosis
• Major clinical form:
rhino-cerebral mucormycosis
• Germination of sporangiospores in the nasal passages and invasion of hyphae into the blood vessels causing thrombosis, infarction, and necrosis
• Invasion: sinuses, eyes, cranial bones, brain
Rhinocerebral mucormycosis
Vesicle is conical-shaped
Phialides are arranged in single row
Conidia arise from upper third of vesicle
Conidia are hyaline
A fumigatus
• Vesicle is globular-shaped
• Phialides in one or two rows
• Conidia arise from upper two-third to entire vesicle
• Conidia are hyaline
A flavus
Vesicle is globular-shaped Phialides in two rows
Conidia arise from entire vesicle
Conidia are black in color
A niger
Candida glabrata assimilated (2);
glucose and trehalose
C. krusei assimilated_____ only.
glucose
_____is assimilated only by Candida kefyr.
Lactose
assimilation is positive for C. tropicalis which differentiates it from C. albicans and C. parapsilosis.
Cellobiose
is not assimilated by these Candida species.
Dulcitol
C. albicans
Green-blue
Metallic blue with pink halo
C. tropicalis
Mauve
C. glabrata
Pink and fuzzy
C. krusei
Light blue with blue halo
C. auris (Front)
Light blue with blue halo
C. auris (Back)
