Opportunistic Mycosis Aspergilosis

Question 1

follows particularly heavy and repeated exposure to larger number of spores

Answer 1

Allergic alveolitis

Question 2

causes allergic alveolitis, who handle barley on which A.claveushas sporulatedduring malting process

Answer 2

Malsters lung

Question 3

colonized pre-exiting cavities to form a mass of mycelium, as “fungus ball” on X-ray

Answer 3

Aspergilloma

Question 4

infection can spread to the orbit of the eye and to the brain, common in Sudan

Answer 4

Para nasal asoergilloma

Question 5

Allergic Bronchopulmonary Disease –Spore Inhalation-Asthma or Other allergic symptoms –Atopic Persons –Elevated IgE , Eosinophilia

Answer 5

Hypersensitivity aspergillosis or pneumonitis type 1

Question 6

Develop :Heavy & repeatedexposure to larger number of spores

Answer 6

Allergic Alveolitis( Type III

Question 7

Form of Allergic Alveolitis caused byAspergillus claveus –from barley containing spore s

Answer 7

Malsters lung

Question 8

Ball-like Masses of Hyphae/Mycelium -Enclosed Dense Fibrous CT-Form in Cavities resulting from previous PTB

Answer 8

Non invasive aspergillosis

Question 9

A fungal ball /fungus will colonized pre-existing (Tuberculosis ) cavities in the lung and form compact ball of Mycelium which is later surrounded by dense fibrous wall

Answer 9

Aspergiolloma

Question 10

occurs due to invasion of blood vessels

Answer 10

Haemoptysis

Question 11

occurs in immunocompromisedwith underlying disease•Neutropenia-Most common predisposing factor •A.fumigatusis the most common infecting species

Answer 11

Invasive aspergillosis

Question 12

Paranasal Granulomas-A.flavus, A.fumigtusMay invade paranasalsinuses spread Bone Orbit of eyeBrain

Answer 12

Paranasal Sinuses, Ear Canal Aspergilloma

Question 13

Most common cause of para nasal

Answer 13

Fungal Sinusitis

Question 14

Fungus balls : External Auditory canal

Answer 14

Otomycosis

Question 15

Skin trauma Dissemination : Lungs to skin -Immunocompromised patients-Raised, red papules Necrotic

Answer 15

Cutaneous aspergillosis

Question 16

Involves major Organ Systems -AIDS -Seen IV Drug Users -Abscesses –Brain, heart, kidneys, bones & GIT.-Systemic Involvement –often Fatal especially when brain is involved

Answer 16

Systemic aspergillosis

Question 17

Contaminated food

Answer 17

Mycotoxicoses

Question 18

Blood infection

Answer 18

True aspergillosis

Question 19

Rare complication of aspergillosis

Answer 19

Endocarditis

Question 20

Sabouraud Dextrose Agar

Answer 20

Velvety to powdery Surface
-Aspergillus fumigatus 
-Dark green
-Aspergillus niger 
–Black-Aspergillus flavus 
–Yellow-Green

Question 21

Prevent Relapse in Immunocompromised

Answer 21

Itraconazole

Question 22

Surgical removal of Aspergillomas & surrounding tissues

Answer 22

High Dose IV Amphotericin B + Other antifungal

-Voriconazole –Aspergillus terreus

Question 23

Hypersensitivity

Answer 23

Anti-Histamines & Desensitization to allergens

Question 24

Atopic individuals, with elevated IgElevels•10-20% of Asthmatics react to A.fumigatus

Answer 24

Allergic aspergillosis