Opioids/LAs/NSAIDs drugs

Question 1

Morphine

Answer 1

Mu or Kappa agonist
Opium alkaloid
Can stimulate histamine release when give IV
Lasts around 4 hours for pain

Question 2

Codeine

Answer 2

Mu agonist
Opium alkaloid
Generally used as an anti-tussive, only a mild analgesic.
May be used in combination with acetaminophen

Question 3

Hydromorphone

Answer 3

Mu agonist
Synthetic opioid
5-7x more potent than morphine and with a faster onset
Less of negative side effects (histamine, emesis, etc)

Question 4

Fentanyl

Answer 4

Mu agonist
Synthetic opioid
100x more potent than morphine 
Short half life = use patch of lozenges 
Paradoxical excitement in horses

Question 5

Etorphine

Answer 5

Mu, kappa, and delta agonist
1000x more potent than morphine
Generally used as a tranquilizer in darts

Question 6

Buprenorphine

Answer 6

Partial Mu agonist and K antagonist
Used with just mild to moderate pain
Can facilitate withdrawal with opioid agonist