Opioids

Question 1

Opioids

Answer 1

bind to opioid receptors in CNS causing inhibition of ascending pain pathways and causing CNS depression

indications:
- MI
- trauma
- post-op
- cancer
- kidney stones
- sickle cell crisis
- back pain

adverse effects:

• CNS depression
• constipation
• hypotension

Question 2

Buprenorphine

Answer 2

partial opioid agonist

Question 3

Naloxone

Answer 3

opioid antagonist
used for opioid overdose
causes release of catecholamines which cause withdrawl symptoms or unmask pain

Question 4

Naltrexone

Answer 4

opioid antagonist
reduces urge to use opioids and alcohol

lowers opioid threshhold, so patients may OD if they try and use opioids