Opioids

Question 1

Normal processing of stimuli that damages normal tissues; how pain becomes conscious; responsive to non-opiioids and opioids is what type of pain?

Answer 1

Nociceptive Pain

Question 2

Abnormal processing of sensory input by the PNS or CNS; treatment includes adjuvant analgesics

Answer 2

Neuropathic Pain

Question 3

mu agonists & mixed agonist-antagonists is what type of analgesic?

Answer 3

Opioids

Question 4

Multipurpose & specific to type of pain is what type of analgesic?

Answer 4

Adjuvants

Question 5

This schedule can not be prescribed, research only. (ex. heroin, medical marijuana)

Answer 5

Schedule I

Question 6

This schedule is more likely to be abused. (ex. codeine, morphine, fentanyl, meperidine, hydromorphone, etc)

Answer 6

Schedule II

Question 7

This schedule is safer, less likely to be abused. (ex. combination products w/ codeine)

Answer 7

Schedule III

Question 8

This schedule is proven to be as effective as acetaminophen. (ex. benzodiazepines, tramadol)

Answer 8

Schedule IV

Question 9

This schedule might help a cough

Answer 9

Schedule V

Question 10

What are the 3 types of morphine products?

Answer 10

MS Contin, MSIR, Avinza/Kadian

Question 11

Which morphine product provides 24 hr control of pain?

Answer 11

Avinza/Kadian

Question 12

What is the brand name for hydromorphone? hydromorphone ER?

Answer 12

Dilaudid, Exalgo

Question 13

What are the 2 oxycodone products?

Answer 13

Oxycontin and Percocet

Question 14

What is percocet made of?

Answer 14

Oxycodone + APAP

Question 15

T or F: Oxycontin should never be used in acute pain?

Answer 15

True. Use percocet for acute pain instead

Question 16

What is the brand name for the Fentanyl Patch?

Answer 16

Duragesic

Question 17

What is the most potent opioid on the market? What does the pupils look like?

Answer 17

Fentanyl patch

pupils = miosis

Question 18

What is the brand name for the Fentanyl Lozenge? What is it used for?

Answer 18

Actiq

Use for someone with mouth/esophangyl cancer, pts who have trouble swallowing, or someone in hospice care

Question 19

What is the weakest opioid analgesic?

Answer 19

Codeine

Question 20

What opioid has the most affinity for plugging into the chemo-affinity zone?

Answer 20

Codeine

Question 21

Tylenol #3 is composed of what?

Answer 21

Codeine + APAP

Question 22

Vicodin is composed of what 2 things?

Answer 22

Hydrocodone + APAP

Question 23

What is the main ADR of vicodin?

Answer 23

Liver enzyme changes

Question 24

What hydrocodone product was a C3 but is now a C2?

Answer 24

Vicodin!

all hydrocodone products are C2

Question 25

What is a the brand name of Meperidine? Is it a good or bad opioid?

Answer 25

Demerol Terrible Opioid!

Question 26

What opioid analgesic can be used in morphine allergic patients?

Answer 26

Meperidine

Question 27

What is the main ADR of using meperidine? What are the side effects?

Answer 27

Contains active metabolites Causes CNS changes, seizures, visual issues, twitching, anxiety

Question 28

What is the brand name for Methadone?

Answer 28

Dolophine

Question 29

What are the 2 uses for methadone?

Answer 29

1. Opioid Abuse Treatment | 2. Chronic Pain

Question 30

Methadone has __ humps. The alpha hump helps in _____. The beta humps help with _______.

Answer 30

2 humps, chronic pain, opioid abuse treatment

Question 31

What is the brand name of Tramadol?

Answer 31

Ultram

Question 32

T or F: Opioid addicts take high doses of tramadol to cover them until their next dose so they won't go through withdrawal.

Answer 32

True

Question 33

Tramadol has a dual mechanism of action that plugs into a ___ and ____ receptor.

Answer 33

mu and neurotransmitter

Question 34

What are the side effects of tramadol?

Answer 34

Lowers seizure threshold, give pt constipation

Question 35

What are the main 5 ADRs of opioids?

Answer 35

1. Constipation 2. Pruritis 3. Nausea/Vomiting (pseudoallergy) 4. Inhibition of cough reflex 5. Miosis

Question 36

What are the 2 opioid antagonist? What is the MOA?

Answer 36

Naloxone (Narcan) and Naltrexone (Revia) Naloxone removes morphine from receptors/ nalaxone replaces morphine on receptors

Question 37

What are opioid antagonist used for?

Answer 37

Pts who overdosed on opioids

Question 38

What is a type of mixed opioid agonist-antagonist? What is it used for?

Answer 38

Suboxone - used for opioid addiction, replacement for methadone treatment

Question 39

Definition: Compulsive use despite harm

Answer 39

True Addiction

Question 40

Definition: Escalation of dose to maintain effect

Answer 40

Tolerance