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Pharm 3 > Opioids > Flashcards

Opioids Flashcards

1
Q

Normal processing of stimuli that damages normal tissues; how pain becomes conscious; responsive to non-opiioids and opioids is what type of pain?

A

Nociceptive Pain

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2
Q

Abnormal processing of sensory input by the PNS or CNS; treatment includes adjuvant analgesics

A

Neuropathic Pain

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3
Q

mu agonists & mixed agonist-antagonists is what type of analgesic?

A

Opioids

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4
Q

Multipurpose & specific to type of pain is what type of analgesic?

A

Adjuvants

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5
Q

This schedule can not be prescribed, research only. (ex. heroin, medical marijuana)

A

Schedule I

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6
Q

This schedule is more likely to be abused. (ex. codeine, morphine, fentanyl, meperidine, hydromorphone, etc)

A

Schedule II

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7
Q

This schedule is safer, less likely to be abused. (ex. combination products w/ codeine)

A

Schedule III

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8
Q

This schedule is proven to be as effective as acetaminophen. (ex. benzodiazepines, tramadol)

A

Schedule IV

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9
Q

This schedule might help a cough

A

Schedule V

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10
Q

What are the 3 types of morphine products?

A

MS Contin, MSIR, Avinza/Kadian

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11
Q

Which morphine product provides 24 hr control of pain?

A

Avinza/Kadian

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12
Q

What is the brand name for hydromorphone? hydromorphone ER?

A

Dilaudid, Exalgo

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13
Q

What are the 2 oxycodone products?

A

Oxycontin and Percocet

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14
Q

What is percocet made of?

A

Oxycodone + APAP

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15
Q

T or F: Oxycontin should never be used in acute pain?

A

True. Use percocet for acute pain instead

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16
Q

What is the brand name for the Fentanyl Patch?

A

Duragesic

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17
Q

What is the most potent opioid on the market? What does the pupils look like?

A

Fentanyl patch

pupils = miosis

18
Q

What is the brand name for the Fentanyl Lozenge? What is it used for?

A

Actiq

Use for someone with mouth/esophangyl cancer, pts who have trouble swallowing, or someone in hospice care

19
Q

What is the weakest opioid analgesic?

A

Codeine

20
Q

What opioid has the most affinity for plugging into the chemo-affinity zone?

A

Codeine

21
Q

Tylenol #3 is composed of what?

A

Codeine + APAP

22
Q

Vicodin is composed of what 2 things?

A

Hydrocodone + APAP

23
Q

What is the main ADR of vicodin?

A

Liver enzyme changes

24
Q

What hydrocodone product was a C3 but is now a C2?

A

Vicodin!

all hydrocodone products are C2

25
Q

What is a the brand name of Meperidine? Is it a good or bad opioid?

A

Demerol

Terrible Opioid!

26
Q

What opioid analgesic can be used in morphine allergic patients?

A

Meperidine

27
Q

What is the main ADR of using meperidine? What are the side effects?

A

Contains active metabolites

Causes CNS changes, seizures, visual issues, twitching, anxiety

28
Q

What is the brand name for Methadone?

A

Dolophine

29
Q

What are the 2 uses for methadone?

A
  1. Opioid Abuse Treatment

2. Chronic Pain

30
Q

Methadone has __ humps. The alpha hump helps in _____. The beta humps help with _______.

A

2 humps, chronic pain, opioid abuse treatment

31
Q

What is the brand name of Tramadol?

A

Ultram

32
Q

T or F: Opioid addicts take high doses of tramadol to cover them until their next dose so they won’t go through withdrawal.

A

True

33
Q

Tramadol has a dual mechanism of action that plugs into a ___ and ____ receptor.

A

mu and neurotransmitter

34
Q

What are the side effects of tramadol?

A

Lowers seizure threshold, give pt constipation

35
Q

What are the main 5 ADRs of opioids?

A
  1. Constipation
  2. Pruritis
  3. Nausea/Vomiting (pseudoallergy)
  4. Inhibition of cough reflex
  5. Miosis
36
Q

What are the 2 opioid antagonist? What is the MOA?

A

Naloxone (Narcan) and Naltrexone (Revia)

Naloxone removes morphine from receptors/ nalaxone replaces morphine on receptors

37
Q

What are opioid antagonist used for?

A

Pts who overdosed on opioids

38
Q

What is a type of mixed opioid agonist-antagonist? What is it used for?

A

Suboxone - used for opioid addiction, replacement for methadone treatment

39
Q

Definition: Compulsive use despite harm

A

True Addiction

40
Q

Definition: Escalation of dose to maintain effect

A

Tolerance

Pharm 3 (5 decks)

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