Opioids Flashcards
What are the 3 strong opioids?
Morphine
Methodone
Meperidine
What are the 2 moderately strong opioids?
Codeine
Oxycodone
What are the 2 receptor agonist-antagonist drugs?
pentazocine
buprenorphine
What is the one opioid antagonist?
naloxone
When is morphine indicated?
- pain in MI
- pain in sickle cell crisis
- pain in surgery
- pain with trauma
- chronic pain
- pain from kidney stones
- severe back pain
What are 3 side effects of morphine?
1) constipation
2) addiction
3) tolerance
When is Meperidine indicated?
to relieve spasmotic effects (biliary spasm, renal colic)
What are side effects of Meperidine?
Serotonin seizure respiratory depression dysphoria tremor
When is hydrocodone indicated?
treats moderate to severe pain (mu receptor, delta receptor)
When is codeine indicated?
mild to moderate pain
cough
diarrhea
IBS
narcolepsy
When is pentazocine used?
dental extraction
What is an important side effect of pentazocine?
weakly antagonizes analgesic effects of morphine and meperidine
When is methadone indicated?
to control intractable cough associated with terminal lung cancer
