Opioids

Question 0

Pain that lasts 3 months or more, not urgent
Often accompanied by emotional stress
With or without evidence of tissue damage; any part of body

Answer 0

Chronic (noncancer) pain

Question 1

Nerve endings that selectively respond to painful stimuli.

Abundant in arterial walls, joint surfaces, muscles fascia, Pearlstein, skin and soft tissue.

Answer 1

Nociceptors

Question 2

Has characteristics of both acute and chronic pain.

Often caused by tumor spread and the resulting tissue destruction

Answer 2

Cancer pain

Question 3

Pain resulting from stimulation of nociceptors in skin, bone, muscle, and soft tissue
Usually well localized; sharp, burning, gnawing, throbbing or cramping
Ex sprains, arthritis.

Answer 3

Somatic pain.

Question 4

Pain that is diffuse and not well localized
Results from Nociceptors in abdominal or thoracic organs
May be referred
Severe pain may stim PNS, resulting in low bp and pulse, NV and syncope

Answer 4

Visceral pain

Question 5

Pain caused by lesions or physiolgic pain the injure peripheral nerves or the CNS
Severe, shooting, burning, stabbing.
Difficult to treat because analgesics are less effective on CMS pain

Answer 5

Neuropathic pain

Question 6

Mylenated nerve fibers found in skin and muscle

Transmit fast, sharp, well localized pain.

Answer 6

A-delta nerve fibers

Question 7

Mylenated nerve fibers found in muscle tissue, abdominal viscera, and periosteum.
Slow pain signals, poorly localized, dull, burning

Answer 7

C fibers

Question 8

Pain med admin to reduce post surgical pain by using different meds of diff classes to block multiple pain pathways

Answer 8

Pre-emptive analgesia

Question 9

Prototype opioid agonist
P.o., IM, SubQ, IV 
Significant first  pass for P.O. 
Closes gates in brain and spinal cord
Adv effects: resp depression, euphoria, sedation and slowed GO motility
Addictive

Answer 9

Morphine sulfate