Opioids Flashcards

1
Q

opiates

A

drugs that occur naturally from the opium poppy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

opioids

A

natural, semisynthetic, synthetic, or endogenous substances that bind to the opioid receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

____ is one of the oldest drugs in the world

A

opium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

In the 19th century, Britain went to war against ____ to force them to purchase ___. China lost and had to make significant concessions to the West.

A

China; opium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Opiate addiction skyrocketed during the nineteenth century due to

A

the isolation of morphine
the development of the hypodermic syringe
importation of Chinese laborers
war
popularity of patent medicines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

____ and ____ factors played a key role in the development of laws against opioid use.

A

Racial; socioeconomic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Almost __ million Americans age 12 and older report using prescription pain relievers in the past year, and almost __ million people in the United States report misusing these drugs.

A

83; 10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

The ___ of prescription painkillers has greatly increased in the past few decades

A

nonmedical use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

About _____ people report current use of heroin, although some researchers believe that is an underestimation.

A

431,000

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Heroin use among adolescents and young adults may be increasing due to

A

the availability of cheaper, purer heroin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

opium comes from the ___ and contains morphine, codeine, thebaine, and other substances

A

poppy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

____ is synthesized from morphine by adding two acetyl groups- this makes the substance more ___

A

heroin; lipid-soluble

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

The _____, _____, and _____ affect opioid actions in the body

A

routes of administration; lipid solubility; interactions with other substances

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Opioid routes of administration

A

ingestion, absorbed rectally, sublingually, or transdermally; snorted; smoked; or injected

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Opioids bind to ___ throughout the body.

A

opioid receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Types of opioid receptors include

A

mu
delta
kappa
NOP

17
Q

_____ opioids include enkephalins, endorphins, and dynorphins

A

endogenous

18
Q

Effects of opioids

A

diminish pain
suppress respiration
decrease gastrointestinal activity
increase sleep
cause euphoria
impair cognitive function

19
Q

Thousands of people in the United States die each year of an overdose of opioids. Among those age 24-35, __% of deaths were attributable to opioids

A

20

20
Q

Opioids are used to treat a number of conditions including

A

pain relief/analgesic effects
cough suppressants
alleviate diarrhea

21
Q

The organs are not damaged or destroyed even with long term, heavy use of narcotics. Rather than the direct effects of the drug, it may be the ____ of the addict that is most dangerous.

A

lifestyle

22
Q

____, ____, and ____ tolerance, as well as _____ tolerance, develops in chronic opioid users.

A

Metabolic; cellular; behavioral; cross

23
Q

Opioids are

A

addictive

24
Q

Withdrawal symptoms are typically ____ those of the direct effects of the drug.

A

opposite

25
Q

opioid withdrawal treatment methods

A

naltrexone, methadone, clonidine, and ultra rapid detoxification

26
Q

other opioid addiction treatment programs

A

substitution opioids
therapeutic communities
Narcotics Anonymous
needle exchange programs

27
Q

endorphins

A

a morphine-like substance originating from within the body that blocks pain transmission

28
Q

Harrison Narcotics Act

A

signed into law 1914, this act regulated and taxed the production, distribution, and prescription of opium, morphine, and cocaine

29
Q

narcotic

A

drug that relieves pain, induces sleep, and reduces sensibility

30
Q

Needle Exchange program

A

an intervention program that provides clean needle to IV drug users in return for used syringes, which are destroyed

31
Q

neonatal abstinence syndrome

A

a group of conditions that occur when a baby withdraws from opioid drugs they were exposed to as a fetus

32
Q

nociceptor

A

a sensory receptor for painful stimuli

33
Q

opioid triad

A

coma, depressed respiration, pinpoint pupils (indicative of opioid poisoning)