Opioid doses

Question 1

Sufentanil epidural dose

Answer 1

10-15mcg/kg in 10mL 0.125% bupivacaine

Question 2

Sufentanil sedation dose

Answer 2

Load: 0.1-0.5mcg/kg
Infusion: 0.005-0.01mcg/kg/min

Question 3

Sufentanil GA minor procedure

Answer 3

Load: 1-2mcg/kg
10-50mcg PRN

Question 4

Sufentanil GA moderate procedure

Answer 4

Load: 2-8mcg/kg
10-50mcg PRN
Infusion: 0.3-1.5mcg/kg/h

Question 5

Sufentanil GA major procedure

Answer 5

Load: 8-30mcg/kg
10-50mcg PRN
Infusion: 0.5-2.5mcg/kg/h

Question 6

Fentanyl Epidural

Answer 6

10-100mcg or
mixed in local anesthetic 2-10mcg/mL

Question 7

Fentanyl Intrathecal

Answer 7

10-25mcg

Question 8

Fentanyl sedation/analgesia

Answer 8

Load: 0.5mcg/kg
Maint: 0.01-0.04mcg/kg/h

Question 9

Fentanyl GA adjunct

Answer 9

Bolus: 2-20mcg/kg
Infusion: 2-10mcg/kg/h
High dose: 20-50mcg/kg
Cardiac dose: up to 150mcg/kg as
sole GA agent

Question 10

Fentanyl intubation adjunct

Answer 10

1-3mcg/kg

Question 11

Fentanyl postop

Answer 11

0.5-1.5mcg/kg

Question 12

Remifentanil induction

Answer 12

1-3mcg/kg over 1 minute

Question 13

Remifentanil sedation

Answer 13

Load: 0.1-1mcg/kg over 30-60 sec
Maint: 0.025-0.2mcg/kg/min

Question 14

Remifentanil GA adjunct

Answer 14

Bolus: 0.5-2mcg/kg
Load: 0.5-1mcg/kg
Maint: 0.05-2mcg/kg/min

Question 15

Hydromorphone analgesic

Answer 15

Adult: 0.4-2mg (IV)
Peds: 0.005-0.02mg/kg (IV)

Question 16

Hydromorphone PCA dosing

Answer 16

Adult:
Demand: 0.2-0.6 mg q 5-15min
Basal: 0-0.2 mg/h
Peds:
Demand: 0.005-0.02mg/kg q6-
20min
Basal:0-0.005mg/kg/h

Question 17

Oxycodone immediate release

Answer 17

5-15mg q 4-6 hours

Question 18

Oxycodone controlled release

Answer 18

10mg q8-12 hours

titrate 25-50% q1-2 days

Question 19

Methadone

Answer 19

2.5-10mg (po) q8-13h
2.5-5mg (IV,IM,SC) q8-12 h

titrate up q3-5 days

Question 20

Hydrocodone

Answer 20

2.5-10mg q4h

morphine 10mg = hydrocodone 5-10mg

Question 21

Morphine epidural

Answer 21

Adult:
Bolus: 2-6mg q8-24h
Infusion: 0.2-1 mg/h
Peds:
Bolus: 0.03-0.05 mg/kg (MAX:
0.1mg/kg or 5mg/24h)
Infusion:

Question 22

Morphine sedation/analgesia

Answer 22

2-20mg (IV,IM,SC) q2-4h

Question 23

Morphine intrathecal

Answer 23

Adult: 0.1-0.5mg
Peds: 0.01mg/kg

Question 24

Morphine PCA

Answer 24

Adult:
Bolus: 1-4mg q6-20min
Basal: 0-1mg/h
Peds:
Bolus: 0.01-0.03mg/kg q6-20min
Basal: 0-0.03mg/kg/h

Question 25

Meperidine postop shivering

Answer 25

12.5-25mg (IV)

Question 25

Meperidine sedation/analgesia

Answer 25

Adult: 50-150mg (IV,IM) q3-4h Peds: 0.5-2mg/kg

Question 26

Codeine

Answer 26

Adult: 15-60mg q4-6h (MAX: 120mg) Peds: 1-1.5mg/kg/day divided q4-6h 2-6 MAX: 30mg/day 6-12 MAX: 60mg/day

Question 27

Buprenorphine Epidural

Answer 27

0.3 mg

Question 28

Buprenorphine Intrathecal

Answer 28

0.15 mg

Question 29

Buprenorphine

Answer 29

Adult: 0.3-0.4mg (IV,IM) q6-8h may repeat in 30-60 min x 1 *doses greater than 0.3mg/dose should be given IM* Peds: 2-12: 2-6mcg/kg (IV,IM) q4-6h (MAX: 6mcg/kg/dose) >13: 0.3mg (IV,IM) q6-8h (MAX: 300mg/dose)

Question 30

Naloxone opiate overdose

Answer 30

Adult: 0.2-4mg (IV) q2-3 min PRN (MAX:10mg) then 0.4mg/h titrate to effect Peds: >5or>20kg: 2mg/dose q2-3min PRN, then 0.4mg/h titrate to effect birth-5 or <20kg: 0.1mg/kg (IV) titrated q2-3min PRN

Question 31

Naloxone reversal of opiate respiratory depression

Answer 31

Adult: 0.04-0.4mg doses (IV) titrated 2-3min, infusion load 5mcg/kg followed by 2.5-160mcg/kg/h Peds: >5 or >20kg: 1-10mcg/kg (IV) titrated 2-3min up to 0.4mg

Question 32

Naloxone opiate-induced pruritus

Answer 32

0.25mcg/kg/h