Opiods Flashcards
What are the drugs in the phenanthrene class?
Which receptor do these work on?
morphine
Dilaudid
codeine
oxycodone
Percocet
MD COP
Mu
What are the strong agonist drugs in the phenanthrene drug class?
morphine
Dilaudid
heroin
What are the moderate to mild agonist in the phenanthrene drug class?
codeine
oxycodone
Percocet
COP
Which drug is in the Phenylheptylamine drug class?
What is it used for?
Methadone
used for chronic pain with morphine tolerance and for opioid abuse
What are the drugs in the Phenylpiperidine drug class?
strong agonist:
fentanyl
meperidine (Demerol)
weak agonist:
tramadol
which drug can kill an elephant?
carfentanil
Demerol uses and side effects:
used for post-op shivering
side effects:
* antimuscarinic effects = tachycardia
* negative inotrope= fast HR not strong
* can cause serotonin syndrome
* can cause seizures in people predisposed
Imodium (Loperamide) is what kind of agonist?
What is it used for?
moderate agonist
used for diarrhea
low abuse rate but can be abused if taken with Quinidine(antiarrhythmic)
Buprenorphine(Buprenex) is used for?
what kind of agonist?
to treat opioid abuse-partial agonist
Butorphanol( Stadol) is used for?
what kind of agonist?
pain
post-op shivering
partial agonist
Dextromethorphan is used for
antitussive
weak agonist
naloxone MOA
Mu opioid receptor antagonist
used for opioid reversal
Naltrexone is used for
alcohol withdrawal
caution in people taking morphine
naloxegol is used for:
morphine derivative used to treat constipation caused by opioids.
mu receptors are what type of receptor?
Agonist binding to Mu does what?
GPCR
sedation
inhibition of respiration
